Test 2 Version B

Question 1

Induction of ventromedial portion of the somite to become sclerotome is caused by

Answer 1

SHH

Question 2

1. Listed below cells are neural crest derivatives, except:

Answer 2

Osteocytes

Question 3

Dermatomyotom region of the somite is marked by

Answer 3

PAX3

Question 4

Holt-oram syndrome is caused by mutation in the gene:

Answer 4

TBX5

Question 5

Trisomy 18 causes:

Answer 5

Edwards syndrome

Question 6

In the human embryonic development occurs

Answer 6

Blastocyte

Question 7

If the neural tube fails to close in the cranial region, the defect is called:

Answer 7

Anencephaly

Question 8

Urogenital structures develop from:

Answer 8

Intermediate mesoderm

Question 9

Respiratory distress syndrome develops as a result of:

Answer 9

Deficiency of surfactant

Question 10

Indicate the homeobox-containing transcription factor responsible for establishing left-sideness of the embryo

Answer 10

PITX2

Question 11

In the scheme of primary ovary follicle with the arrow is indicated:

Answer 11

Theca interna- points into the white line(inner membrane)

Question 12

Epithelial lining of the primitive gut develops from:

Answer 12

Endoderm

Question 13

Indicate the inhibitor of BMP in the process of neural induction:

Answer 13

Chordin

Question 14

In the process of pancreas development, SHH expression in the gut endoderm destined to form the dorsal pancreatic bud is repressed by:

Answer 14

FGF2

Question 15

Indicate the transcription factor promoting crest cell migration from the neuroectoderm:

Answer 15

SLUG

Question 16

In the kidney development, the process of branching and growth of the uretic buds is stimulated by

Answer 16

HGF

Question 17

Indicate gene important for designating the forebrain and midbrain:

Answer 17

LIM1

or OTX2 (Version A)

Question 18

Disease being an example of trinucleotide repeat disorders:

Answer 18

Fragile x syndrome

Question 19

Indicate a primary brain vesicle:

Answer 19

Mesencephalon

Question 20

Development of the cerebellum is regulated by:

Answer 20

EN2

Question 21

Apert syndrome is caused by mutation in the gene:

Answer 21

FGFR2

Question 22

Indicate receptors for WNT proteins (WNT signaling pathway);

Answer 22

Frizzled family of proteins

Question 23

In the process of spermatogenesis, in the result of meiosis 1 are formed:

Answer 23

Secondary spermatocytes

Question 24

In the kidney development, conversion of the mesenchyme to an epithelium for nephron formation is regulated by:

Answer 24

Nodal

Question 25

Indicate the transcription factor specifying the esophagus and stomach (inducing development of esophagus and stomach):

Answer 25

SOX2

Question 26

Human morula consist of:

Answer 26

16 cells

Question 27

Polysperm is prevented by:

Answer 27

Cortical reactions

Question 28

Indicate disease developing when neural crest cells fail to migrate

Answer 28

Congenital megacolon

Question 29

A condition in which transposition of the viscera in the thorax and abdomen occurs, called:

Answer 29

Situs inversus

Question 30

In the diagram are shown changes in a hormone concentration in peripheral blood during the menstrual cycle. This hormone is:

Answer 30

FSH