Test 2 Parenteral Nutrition Flashcards

1
Q

Why don’t we start with the full % of dextrose that we want?

A

it will give the pt hyperglycemia because the endogenous insulin hasn’t been able to keep up yet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How do we reach the level of dextrose that we want?

A

increasing in increments of 2-2.5% as pt tolerates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Maximum dextrose %

A
  • PIV: 12.5%

- Central: 25-30%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

dextrose nutritional contribution

A

3.4kcal/gram

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

amino acids nutritional contribution

A

4kcal/gram

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

lipid nutritional contribution

A
  • 10kcal/gram
  • for 10%: 1.1kcal/mL
  • for 20%: 2kcal/mL
  • for 30%: 3kcal/mL
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

initiation of lipids

A
  • 0.5-1 gram/kg/day
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Distribution of calories with protein

A
  • Dextrose: 40-60%
  • Amino acids: 7-15%
  • Lipidsi: 30-50%
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Distribution of calories without protein

A
  • Dextrose: 50-70%

- Lipids: 30-50%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Phosphorous amount in KPhos

A

0.68mmol phosphate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Phosphorous amount in NaPhos

A

0.75mmol phosphate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Problem with calcium / phosphorous stability

A
  • precipitation can occur
  • calcium gluconate more stable
  • add phosphate salts early; add calcium at end
  • limit amount of Ca/Phos due to osteopenia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

formulations of sodium

A
  • Sodium Chloride (NaCl)
  • Sodium Acetate (NaAc)
  • Sodium Phosphate (NaPhos)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

formulations of potassium

A
  • Potassium Chloride (KCl)
  • Potassium Acetate (KAc)
  • Potassium Phosphate (KPhos)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

formulations of calcium

A

Calcium Gluconate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

formulations of magnesium

A

Magnesium Sulfate

17
Q

osmolarity limits in PIV

A

900-1100 mOsm/L

18
Q

potassium limits in PIV

A

40 mEq/L

19
Q

advantages of PIV

A
  • rapid access

- less invasive: not meant to be there for a long period of time (7 days or shorter)

20
Q

disadvantages of PIV

A
  • cannot meet caloric needs (due to osmolarity limitations)
  • Hypertonic formulations can cause phlebitis
  • Extravasation of PN: results in damage to tissue, scarring
21
Q

osmolarity limits in central line

A

no limits

22
Q

potassium limits in central line

A

120mEq/L

23
Q

advantages of central line

A
  • suited for longer duration use
  • can meet nutritional requirements
  • decreased risk of phlebitis or extravasation
24
Q

disadvantages of central line

A
  • Risk of infection with line

- Catheter-induced trauma

25
Q

What are the types of complications that can occur with PN?

A
  • mechanical and technical
  • infection
  • metabolic and nutritional
26
Q

mechanical and technical complications with PN

A
  • infusion pump failure

- catheter-related complications

27
Q

infection complications with PN

A
  • catheter-related infections

- typically gram + infections

28
Q

metabolic and nutritional complications with PN

A
  • PNALD: Parenteral nutrition associated liver disease
  • Hypertriglyceridemia
  • Hyperglycemia
  • Refeeding syndrome
29
Q

PNALD

A
  • Increase in total bilirubin, direct bilirubin, AST, ALT, Alkaline phosphatase
  • Characterized by direct bilirubin > 2 mg/dL
  • MANAGEMENT: cycle TPN, supplement with omega-3 fatty acids, start trophic feeds if possible
30
Q

Hypertriglyceridemia

A
  • Adults > 400 mg/dL
  • Infants and children > 200-250 mg/dL
  • MANAGEMENT: Hold or decrease lipid infusion, Consider decreasing rate of glucose infusion if excessive
31
Q

Hyperglycemia

A
  • Adults > 180 mg/dL
  • Infants and children > 150 mg/dL
  • MANAGEMENT: Decrease rate of dextrose infusion, Use intermittent or continuous infusion insulin
32
Q

Refeeding syndrome

A
  • occurs in malnourished pts when started on aggressive nutrition treatment
  • rapid decrease in serum phos, K, Mg
  • MANAGEMENT / prevention: identify high risk pts, start slow, advance slowly, increase amount of phos, K, and Mg in PN