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1
Q

1st murderer caught using dna analysis

A

colin pitch forch- jeffereys solved it by dna anlysis he’s a genetic professor at the university of leicester.

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2
Q

codis data base started in

A

1998

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3
Q

fbi starts dna casework in us- national DNA index system (NDIS) launched

A

1988

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4
Q

first american convicted using dna evidence

A

tommie lee andrews 1987.

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5
Q

mid-1990s the general public is largely made aware of this new technology of DNA profiling thanks tto the media coverage

A

of o.j. simpson.

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6
Q

what does the FBIS CODIS database stand for

A

combined dna index system

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7
Q

what is codis used for

A

used for linking serial crimes and unsolved cases with repeat offenders. launched in 1998. links all 50 states.

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8
Q

how many core STR markers are needed for the FBI CODIS DNA DATABASE

A

20 core STR markers. increase from the original 13 efffective in 2017. mmany were STR loci already used in europe, making the sharing of DNA profiles internationally more straightforward.

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9
Q

AMEL stands for and is located onXY chromsomes and analyzed to deteterimine and individuals_____

A

amel= amelogenin
XY= biological sex of the individual

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10
Q

STR is

A

short tandem repears are also known as microsatellites.

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11
Q

an str is a specific _____ that repeats consectively from______

A

a specific sequence of bases that repeats consecutibely from ~5-50 times

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12
Q

STRS can be located at __________ that are within the human genome.

A

strs can be located at thousands of locations within the human genome.

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13
Q

research has shown that these non-coding DNA regions have a higher rate of _____________compared to other regions of our DNA which leads to more genetic ____

A

higher rate of mutation compared to other regions of our dna, which leads to genetic diversity more among humans

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14
Q

STR analysis has multiple uses including:

A

DNA profiling for fmaily relatedness, Forensic DNA alaysis, and population genetics

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15
Q

the repeat region is a variable between samples while the flanking regions are ________

A

constant.

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16
Q

homozygote (STRS) vs heterozygote STRs

A

homozygous=both alleles are the same length
heterozygote=alleles differ and can be resolved from one another.

17
Q

human identity testing with multiplex strs: two different individuals: each peak represents a different___

A

a different allele

18
Q

human identity testing with multiplex STRS 1 peak per loci

A

homozygous

19
Q

human identity testing with multiplex strs 2 peak per loci

A

2 peaks =hereozygous

20
Q

probability of a random math in human identity testing with multiplex STRs

A

~1in 3 trillion.

21
Q

human identity testing with multiplex strs. results obtained in less than ___ hours the size of a ___

A

in less than 5 hours. pinhead size.

22
Q

biological sex identification using STR

A

2 peaks= heterozygous= XY=male
1 peak=homozygous= XX= female.

23
Q

the innocence projecti n 1992

A

exonarates the wrongfully convicted through DNA testing and reforms the criminal justice system to prevent future injustics. proves their innocence

24
Q

is someone working to use DNA sequence information to determine physical characteristics of an indiv including eye, hair and skin color.?

A

yes for the future. dr. susan walh at perdue university is.

25
Q

can you determine an individual’s age based on methylation levels in a person’s DNA?

A