test Flashcards
1st murderer caught using dna analysis
colin pitch forch- jeffereys solved it by dna anlysis he’s a genetic professor at the university of leicester.
codis data base started in
1998
fbi starts dna casework in us- national DNA index system (NDIS) launched
1988
first american convicted using dna evidence
tommie lee andrews 1987.
mid-1990s the general public is largely made aware of this new technology of DNA profiling thanks tto the media coverage
of o.j. simpson.
what does the FBIS CODIS database stand for
combined dna index system
what is codis used for
used for linking serial crimes and unsolved cases with repeat offenders. launched in 1998. links all 50 states.
how many core STR markers are needed for the FBI CODIS DNA DATABASE
20 core STR markers. increase from the original 13 efffective in 2017. mmany were STR loci already used in europe, making the sharing of DNA profiles internationally more straightforward.
AMEL stands for and is located onXY chromsomes and analyzed to deteterimine and individuals_____
amel= amelogenin
XY= biological sex of the individual
STR is
short tandem repears are also known as microsatellites.
an str is a specific _____ that repeats consectively from______
a specific sequence of bases that repeats consecutibely from ~5-50 times
STRS can be located at __________ that are within the human genome.
strs can be located at thousands of locations within the human genome.
research has shown that these non-coding DNA regions have a higher rate of _____________compared to other regions of our DNA which leads to more genetic ____
higher rate of mutation compared to other regions of our dna, which leads to genetic diversity more among humans
STR analysis has multiple uses including:
DNA profiling for fmaily relatedness, Forensic DNA alaysis, and population genetics
the repeat region is a variable between samples while the flanking regions are ________
constant.
homozygote (STRS) vs heterozygote STRs
homozygous=both alleles are the same length
heterozygote=alleles differ and can be resolved from one another.
human identity testing with multiplex strs: two different individuals: each peak represents a different___
a different allele
human identity testing with multiplex STRS 1 peak per loci
homozygous
human identity testing with multiplex strs 2 peak per loci
2 peaks =hereozygous
probability of a random math in human identity testing with multiplex STRs
~1in 3 trillion.
human identity testing with multiplex strs. results obtained in less than ___ hours the size of a ___
in less than 5 hours. pinhead size.
biological sex identification using STR
2 peaks= heterozygous= XY=male
1 peak=homozygous= XX= female.
the innocence projecti n 1992
exonarates the wrongfully convicted through DNA testing and reforms the criminal justice system to prevent future injustics. proves their innocence
is someone working to use DNA sequence information to determine physical characteristics of an indiv including eye, hair and skin color.?
yes for the future. dr. susan walh at perdue university is.
can you determine an individual’s age based on methylation levels in a person’s DNA?
