Test 1- Neuroanatomy, Motor Dev/Sensory tests, Pharmacology, Imaging Flashcards
CNS consists of
Brain, spinal cord, brain stem, and cerebellum
PNS consists of:
Everything else outside the brain/spinal cord
Peripheral sensations are transmitted ___ the _NS via sensory tracts, processed in the ___ and transmitted back to the periphery via ____ tracts.
To the CNS via sensory tracts
Processed in brain
Back to periphery via Motor tracts
A group of nerve fibers that are similar in origin, destination, and function
Tract
Two basic types of nerve cells:
Neurons and Neuroglia
Neurons or Neuroglia?
Specialized for communication through their ability to generate rapid electrochemical signals.
Neurons
Neurons or Neuroglia?
Diverse support cells that facilitate neuron function and survival
Neuroglia
Types of neurons and what they do:
Afferent (sensory)-Project toward a structure/relay to CNS; arrive
Efferent (motor)- Project away from a structure/convey output from CNS to muscles; exit
Interneurons- Relay signals between two neurons
What neurons make up the corticospinal tract, even though they do not innervate muscles?
Upper motor neurons
4 Types of Neuroglia in CNS:
Astrocytes, Oligodendrocytes, Microglia, and Ependymal cells
2 Types of Neuroglia in PNS:
Which is most abundant?
Satellite cells and Schwann cells
Schwann most abundant -contact vasculature and participate in ion buffering; terminal Schwann cells help maintain the neuromuscular junction
*satellite cells buffer extracellular ion concentrations around neuronal cell bodies
Type of Neuroglia in CNS that is responsible for maintaining the capillary endothelium and as such provide a vascular link to neurons. They also contribute to the metabolism of the CNS, regulate extracellular concentrations of ions and neurotransmitters, and proliferate after an injury to create a glial scar.
Astrocytes
Type of Neuroglia in CNS that wrap myelin sheaths around axons, forming the white matter of the CNS
Oligodendrocytes
Type of neuroglia in CNS that Is known as the Phagocytes of the CNS. They engulf and digest pathogens and assist with nervous system repair after injury.
Microglia
Type of Neuroglia in CNS that line the ventricular system and produce and circulate cerebrospinal fluid.
Ependymal cells
Which neurotransmitter influences motor activity, motivation, general arousal, and cognition?
Dopamine
*Parkinson’s, schizophrenia
Which neurotransmitter plays a role in mood, behavior, and inhibits pain?
Serotonin
*Depression, migraines, ADD
Neurotransmitter used by the sympathetic nervous system and produces the “fight or flight”response
Norepinephrine
The neurotransmitter, Acetylcholine, is associated with what disease?
Alzheimer’s
The neurotransmitter GABA is associated with what disease?
Epilepsy
Groupings of cell bodies and dendrites fibers with specialized functions
Gray or white matter?
Gray matter
Myelinated axons
Gray or white matter?
White matter
A bundle of myelinated axons the travel together is called a ___ throughout the body.
Called a ____ in the spinal cord
Called a ____ between the cerebellum and brainstem
Called a ___ in the brainstem
Called a ___ in the brain
Tract throughout body Column in SC Peduncle between cerebellum & brainstem Leminscus in brainstem Capsule in brain
Tracts are named by their ____ and their ____
Origin and destination
What is the primary motor tract for voluntary movement?
Corticospinal tract
The corticospinal tract originates in the ___ and terminates in the ____ ____.
Cortex ; spinal cord
The lateral spinothalamic tract (sensory tract) begins in ___ matter of spinal cord and ascends in lateral cord to terminate in the ____.
Gray matter of SC ; thalamus
Sensory feedback from what sensory tract includes vibration, 2 point discrimination, proprioception, and graphesthesia?
Dorsal column (fasciculus cunneatus and fasciculus gracillis)
Sensory feedback from what sensory tract includes light touch and pressure?
Spinothalamic (Anterior)
Sensory feedback from what sensory tract includes pain and temperature?
Spinothalamic (Lateral)
Order of meninges from outermost to innermost:
Dura mater
Arachnoid
Pia mater
What lobe of the brain is the primary motor cortex and is responsible for judgment, attention, abstract thinking, mood, aggression, and contains Broca’s area? (L hemisphere movements of mouth to produce speech, R hemisphere non-verbal commun.)
Frontal lobe
Which lobe of the brain is the primary sensory cortex in that it attaches meaning and context to the sensory input (is it painful?) and contains the sensory homunculus and stores short-term memory :
Parietal lobe
Which lobe of the brain is the primary auditory cortex and has Wernicke’s area (which interprets all sensory systems including hearing in comprehending spoken language), allows visual perception, musical discrimination, long-term memory, and facial recognition?
Temporal lobe
Which lobe of the brain is the primary visual cortex?
Occipital lobe
Left Brain or Right Brain?
Language, sequential/organized, understanding language, analytical, controlled, logical, rational, math calculations
Left Brain
Left or right brain?
Nonverbal processing, process info in holistic manner, artistic, general concept comprehension, eye-hand coordination, spatial relationships, kinesthetic awareness, music, math reasoning body image awareness
Right Brain
What structure is located deep within white matter of the cerebrum and its functions are voluntary movement, posture, and muscle tone?
Basal Ganglia
A dysfunction in what structure of the brain causes Parkinson’s disease?
Basal ganglia
Deep brain structures:
Function- Primitive emotional reactions (fear, rage, pain, pleasure, affection, sorrow, hunger, thirst, sexual behavior, sleep)
Limbic System (hypothalamus and parts of thalamus, frontal, and temporal lobes)
Deep Brain structures:
Function- Stores new memories and retrieves memories as needed
Hippocampus (located in temporal lobe)
Deep brain structures:
Function- Emotional and social processing
Amygdala (located in temporal lobe)
Deep Brain Structures:
Function- Central relay station for sensory info from periphery and parts of brain to cerebrum
Thalamus
Deep Brain Structures:
Function- Maintains homeostasis, assists in regulating hormones, regulates body temperature
Hypothalamus (deep at base of brain)
What makes up the Brain Stem?
Midbrain, Pons, Medulla
What part of the brain is the relay station between the cerebrum and the spinal cord or cerebellum?
Midbrain
Part of brain stem
What part of the brain controls rate of breathing and orientation of the head in response to visual & auditory output?
Pons
Part of brain stem
What part of the brain controls respiration, heart rate, vomiting, sneezing, and swallowing?
Medulla (part of brain stem)
Located in the ____, the reticular activating system controls levels of ___ and ____ cycles.
In the brain stem
Levels of arousal, sleep wake cycles
What structure of the brain controls balance and complex muscular movement? Major site of motor learning. It learns to carry out anticipatory movements that shift our balance during voluntary movements.
Cerebellum
What might you see in someone with cerebellum lesion?
Gait instability, intention tremor, uncoordinated movements, slurred speech, and difficulty with smooth eye movements
Spinal cord is a continuation of the brain stem and extends to approx the level of the intervertebral disc between the ________vertebrae.
First two lumbar vertebrae
Two primary functions of spinal cord:
Coordination of movement patterns and communication of sensory information
A positive Babinski sign in an adult suggests damage to what?
*Stroking of heel to ball of foot and Great toe extends while others splay out
Damage to corticospinal tract
What would you see in a pt. with a brain stem lesion?
Coordination and movement challenges, speech and swallowing difficulties, sleep issues (sleep apnea)
Muscle spindles are encapsulated ____ receptors that inform the ___ about changes in muscle length.
Sensory receptors
Inform the brain
Anterior horn cells contains neurons that innervate _____ to cause ___.
Skeletal muscle to cause movement
PNS is further divided into the ___ and ____.
Somatic and Autonomic Nervous System
ANS is divided into the ___ and ___ nervous systems
Sympathetic- fight or flight
Parasympathetic- rest and digest