Test 1 meds Flashcards
Acarbose
glucosidase inhibitors
starch blockers
slows down absorption of carbs in small intestine
first bite with each meal
can cause diarrhea, gas, abdominal distention
Dextrose 50%
Glucagon
Exendatide
GLP- 1 agonists
stimulate incretin that releases insulin
injected
slows gastric emptying and increases satiety
risk for pancreatitis
Glargine
long actin insulin
slowly releases insulin into the blood over 24 hours to decrease the rapid rise and fall of glucose levels
Glipizide/ glimepiride
increase insulin production and work on b-cells
risk of hypoglycemia bc too much insulin
15-30 min before meal
stomach pain, heart burn
NPH Insulin
intermediate acting insulin
its cloudy and opaque
usually combines with regular
Regular Insulin
the only short acting
can be given in IV
used mostly for type 1 and DKA
Lispro
rapid onset insulin, most like endogenous insulin. facilitates the uptake of the excess glucose at sites for storage in the liver
use within 15 min of meal
Metformin
most common
Biguanides- reduce glucose production and enhance insulin sensitivity
don’t use with renal disease and IV contrast
Pioglitazone
Thiazolidinediones
effective with insulin resistance
improve insulin resistance and uses it better
black box warning for heart failure
sitagliptin/ saxagliptin
DDP-4 inhibitor
slows the inactivation of incretin that releases insulin
potential hypoglycemia
rapid acting insulin
Lispro, Aspart, Glulisine
onset: 10-30 min
peak: 30 min- 3 hrs
duration: 3-5 hrs
0- 15 min before meal
short acting insulin
Regular insulin
onset: 30-1hr
peak: 2-5 hr
duration: 5-8 hr
30-45 min before meal
intermediate acting insulin
NPH insulin
onset:1.5-4 hr
peak:4-12 hr
duration: 12-18 hr
long acting insulin
Glargine, Detemir, Degludoc
Onset:.8-4 hr
peak: no peak
duration: 16-24 hr
desmopresson
an analog of ADH for Diabetes Insipidus
LOC!!!
octreotide
Acromegaly med
antagonizes effects of GH
must measure GH levels every 2 weeks until optimal dose is found
risk for gallstones, hyperglycemia and don’t take with renal disease
calcium gluconate
used after a thyroidectomy to prevent hypocalcemia after surgery
levothyroxine
for hypothyroidism
must take it regularly and monitor for angina and cardiac
monitor thyroid and adjust along the way
if low- lethargy, sleepy, constipation
if high- tremors, tachycardia, irritable, diarrhea