Test 1 (georgias) Flashcards
- Stochastic effects are usually associated with high dose radiation levels of exposure resulting in cell mutation of death and/or degenerative changes in the tissues exposed.
True
Flase
False
- The effects of ionising radiation on humans and other living tissue is the result of interactions at the ________ level
a. Quantum
b. Atomic
c. Microscopic
d. Macroscopic
b. Atomic
- How would you express what is the lethal dose that would kill fifty percent of the exposed population in thirty days?
a. 50mSv
b. LD 30/50
c. LD50/30
d. 50LD30
c. LD50/30
- A deterministic effect of radiation is
a. Non-reversible
b. A potential effect of long term exposure to radiation
c. Related directly to a high dose of radiation
d. Determined by the kVp selected at the time of exposure
c. Related directly to a high dose of radiation
- A stochastic effect of radiation is
a. A random effect caused by low dose radiation exposure
b. There is usually a threshold below which the effect will not occur
c. Dependant on the amount of fluids in the body
d. Determined by the type of radiation
A random effect caused by low dose radiation exposure
- An example of stochastic effect is:
a. Neurovascular syndrome
b. Cataracts
c. Acute radiation sickness
d. Radiation induced leukaemia
d. Radiation induced leukaemia
- The principle effect behind the ALARA principle is
a. Somatic
b. Deterministic
c. Stochastic
d. Prodromal
c. Stochastic
Match the following classifications with their descriptions
Genetic
Effects appear in the offspring of an individual who received the
agent and the agent was encountered preconception
Match the following classifications with their descriptions
Somatic
The effects appear in the exposed individual
Match the following classifications with their descriptions
Tetratogenic
effects appear in the offspring of an individual who received the agent and the agent was encountered during the gestational period
According to target theory, cell death will only occur if the target molecule is inactivated. What is the target molecule?
a. DNA
b. Glucose
c. Collagen
d. Melatonin
a. DNA
- The response of tissue to radiation is principally a function of which of the following?
a. Fractionation
b. LET
c. Dose
d. RBE
c. Dose
- Which of the following is NOT an example of a deterministic effect?
a. Neurovascular syndrome
b. Cataracts
c. Acute radiation sickness
d. Radiation induced leukaemia
d. Radiation induced leukaemia
- The ionisation of DNA is a result of what type of interactioin?
a. Direct
b. Indirect
c. Free radicals
d. LET radiation
a. Direct
- The ionisation of water molecules can lead to the creation of?
a. LET radiation
b. Carcinogens
c. Free radicals
d. Free energy
c. Free radicals
- The most sensitive stage of a cell for radiation damage is:
a. G1
b. S
c. G2
d. M
d. M
- The least sensitive stage of a cell for radiation damage is:
a. G1
b. S
c. G2
d. M
b. S
- Match the cell type with their relative radiation sensitivity
a. Lymphocytes low
b. Nerve Medium
c. Reproductive High
a. Lymphocytes high
b. Nerve low
c. Reproductive medium
- Which is not a type of DNA mutation?
a. Main-chain scission
b. Cross linking
c. Point lesion
d. Side-chain lesion
d. Side-chain lesion
Radiation-induced damage in tissue:
a. Is lesser in the presence of oxygen
b. Is greater in the presence of oxygen
c. Results only in latent effects
d. Is irreversible
b. Is greater in the presence of oxygen
- The replacement of damaged cells in an organ with fibrotic scar tissue which comprises the function of the organ is an example of:
a. Regeneration
b. Repair
c. Redistribution
d. Tissue necrosis
b. Repair
- Which of the following is not one of the five R’s principles of fractionation that is used in radiation therapy?
a. Redistribution
b. Repair
c. Re population
d. Resonance
d. Resonance
- The exposure of high doses of radiation over brief intervals of time produces _____ effects?
a. Acute
b. Chronic
c. Stochastic
d. Fractionation
a. Acute
- A person exposed to a lethal dose of radiation in excess of 50Gy will invariably die within 48 hours of complications from:
a. Gastrointestinal syndrome
b. Haematopoietic syndrome
c. Neurovascular syndrome
d. Restless leg syndrome
c. Neurovascular syndrome
- If a 20 Sv radiation dose was delivered to a person rapidy, the likely outcome would be?
a. No detachable damage to tissue
b. Some damage to sensitive tissue
c. Significant damage to tissue
d. Death within hours
d. Death within hours
- The LD50/60 for humans is approximately?
a. 1-2mSv
b. 3-5mSv
c. 6-8mSv
d. 9-11mSv
b. 3-5mSv
- The LD50/60 for humans with sensitive medical care may be as high as?
a. 1-2mSv
b. 3-5mSv
c. 6-8mSv
d. 9-11mSv
c. 6-8mSv
- The average annual MRT occupational exposure is:
a. 0.5mSv
b. 1mSv
c. 20mSv
d. 50mSv
a. 0.5mSv
- The annual background radiation in NZ averages:
a. 8mSv
b. 4mSv
c. 2mSv
d. 1mSv
c. 2mSv
- Match the terms with their definition
a)Latent
Initial symptoms that can begin minutes to hours after exposure
b)Manifest illness
Stage that may take weeks to months
Prodromal
Like an incubation period where initial symptoms subside
Recovery
Abrupt onset of moderate to severe symptoms relevant to the underlying organ system damage
Latent = Like an incubation period where initial symptoms subside
Prodromal=Initial symptoms that can begin minutes to hours after exposure
Manifest illness= Abrupt onset of moderate to severe symptoms relevant to the underlying organ system damage
Recovery = Stage that may take weeks to months
- What is fractionation?
a. Technique of giving large doses monthly for radiotherapy
b. Technique of giving one large dose radiotherapy
c. Technique of giving small doses regularly for radiotherapy
d. None of the above
c. Technique of giving small doses regularly for radiotherapy
- Which statement best described haemopoietic syndrome?
a. Rapid onset of neurological and cardiac conditions leading to the loss of consciousness and death
b. Direct damage to the GI tract making the body unable to absorb nutrients and leading to perforation
c. Another name for leukaemia
d. Radiation effects related to blood forming tissues, normally indicated by change in
d. Radiation effects related to blood forming tissues, normally indicated by change in
- Which describes what a point lesion DNA mutation is?
a. Lesion is another name for benign growth
b. Breakage of the backbone of a molecule or DNA strand
c. A disruption of a single chemical bond which is not detectable but can cause malformation within the cell
d. When the side rail on a DNA strand is broken, it may slip and crosslink
c. A disruption of a single chemical bond which is not detectable but can cause malformation within the cell