Test 1: Communication Flashcards
What are the two methods of how cells conduct and process information?
- Binary (on/off)
- Analogue (Continuous, graded, degree)
What determines RMP?
Differing permeability
- K+
- Na+
- Cl-
- Organic anions (A-)
What are the driving forces of RMP?
- Concentration gradient (diffusion)
- Electrical gradient (opposites attract-likes repel)
Do diffusion and electrical gradient use energy?
No, they are passive forces
Na+/K+ pump
Spits out 3 Na+, brings in 2 K+
Draw an action potential
Draw
Saltatory Conduction
Depolarizaiton moving down an axon through myelin sheath to nodes of ranvier.
How is an electrical AP converted to a chemical message?
AP causes Ca2+ channels to open. This causes vesicles of NTs to fuse with the cell membrane and release NT into synaptic cleft
How is a chemical message converted to an electrical message?
NT binds to receptor. Opens ion channels. Ions flow in and either cause depolarization or hyperpolarization
IPSP and EPSP
Inhibitory Post-Synaptic Potential
Excitatory Post-Synaptic Potential
Ion channel that results in an EPSP when opened
Na+
Ion channel that results in an IPSP when opened
K+ and Cl-
Termination of Synaptic Transmission
- Ion channel inactivation
- Enzymatic decay of NT
- Reuptake of NT
- Uptake (by extra-neuronal cells)
- Endocytic internalization of the receptor
- Activation of autoreceptors on presynaptic membrane inhibiting synaptic vesicle exocytosis