Test 1 Circulatory Pathway Flashcards
Plasma
- fluid
- electrolytes
- proteins
- clotting factors
- gases
Serum
- fluid
- electrolytes
- proteins
- gases
Function of erythrocytes
(Red Blood Cells) carry oxygen
Function of platelets
(Thrombocytes) blood clotting
Function of Lymphocytes
(Agranular leukocyte)
T lymphocyte-cell immunity
B lymphocyte-humoral immunity
Function of monocyte
(Agranular leukocyte) phagocytic, precursor to macrophages
Function of neutrophil
(polymorphonuclear leukocytes) phagocytic-kill bacteria
light colored granules
Function of basophil
(base loving) histamine (allergies), heparin (blood thinner)
Contains purple granules
Function of Eosinophils
(acid loving) Fight parasitic worms
Contains red granules
Average Blood Volume
5 liters
Normal hemotocrit
Males: 45% (+/-7%)
Females: 42% (+/- 5%)
Normal Red Blood Count
Males: 5.0x10[6] mm[3]
Females: 4.8x10[6] mm[3]
Difference between anemia and polycemia
Low hemotocrit values may indicate anemia while hight values may indicate polycthemia
Structure of protein hemoglobin
Four polypeptide chaines (2 alpha-a chains & 2 beta chains), each containing a heme unit.
Iron binds in the middle of each heme group.
Life Span of Erythrocytes
105-120 days
Recycling of RBC
Macrophage cells phagocytose RBCs, breaking down hemoglobin. Iron is returned to bone marrow for production of new hemoglobin, bilirubin is transported to the liver, where it is excreted into the intestine as bile.
What hormone is produced by the liver and kidney to control erythropoiesis?
Erythropoietin
What is the immediate precursor to erythrocyte?
Reticulocytes
Normal WBC
4,500-10,000 WBC/microliter
Order of abundance (high to low) of the 5 types of WBC?
Neutrophil, Lymphocyte, Monocyte, Eosinophil, Basophil
What determines blood type?
Antigens on the surface of RBCs
Transfusion Reactions
Type O receives O (universal donor)
Type A receives A & O
Type B receives B & O
Type AB (universal recipient) receives O, A, B, AB
What conditions lead to erythroblastosis fetalis?
Rh- mother pregnant with an Rh+ baby