Test 1

Question 1

Aggregan

Answer 1

The major proteoglycan is cartilage between bones

Question 2

Aneurysm

Answer 2

Abnormal widening or ballooning of a portion of an artery due to weakness in the blood vessel wall

Question 3

Angiogenesis

Answer 3

Formation of new blood vessels

Question 4

Basal Lamina

Answer 4

A layer of the ECM and basement membrane secreted by epithelial cells

Question 5

Basement membrane

Answer 5

A layer of the ECM underlying the epithelium of organs and skin

Question 6

Epithelium

Answer 6

Tissue that forms the outer layer of the body’s surface and lines tubes or cavities in the body

Question 7

Glomerus

Answer 7

A cluster of capillaries in the kidney that filters waste products from the blood and thus initiates urine formation

Question 8

Glycosaminoglycan

Answer 8

Long, linear, highly charged polymer of repeating disaccharides in which many residues often are sulfated

Question 9

Myopia

Answer 9

Nearsightedness

Question 10

Osteogenesis imperfecta

Answer 10

Gentic disorder characterized by bones that break easily

Question 11

Periosteum

Answer 11

Dense fibrous membrane covering the surface of bones except at the joints

Question 12

ABD

Answer 12

Actin binding domain

Question 13

ADF/cofilin

Answer 13

Actin Depolymerizing Factor; actin binding protein that stimulates actin disassembly

Question 14

Arp2/3

Answer 14

Actin Related Protein; actin binding protein that causes actin filaments to branch

Question 15

Filamin

Answer 15

Cross links actin filaments into network

Question 16

Filopodia

Answer 16

Long extension of plasma membrane

Question 17

Fimbrin

Answer 17

Cross links actin filaments in parallel

Question 18

Formin

Answer 18

Actin binding protein that facilitates nucleation of long filaments

Question 19

Lamellopodia

Answer 19

Fan like projections of plasma membrane

Question 20

Profilin

Answer 20

Actin binding protein that stimulates filament assembly by exchanging ADP for ATP

Question 21

Treadmilling

Answer 21

Adding monomers to the + end and removing monomers from the - end of an actin filament, leaving the length unchanged

Question 22

Twinfilin

Answer 22

Helps carry G actin to barbed end of filament

Question 23

WASP/Scar complex

Answer 23

Activator or Arp2/3

Question 24

Axoneme

Answer 24

Fundamental structure of cilia and flagella

Question 25

Basal body

Answer 25

Anchors cilia and flagella to cell

Question 26

Catastrophe

Answer 26

Rapid depolymerization of microtubules that occurs when GTP has been hydrolyzed in all tubulin subunits up to the growing tip

Question 27

Centrosome

Answer 27

Microtubule organizing center in cell

Question 28

Dynein

Answer 28

Motor protein that moves toward minus end of microtubules

Question 29

Kinesin

Answer 29

Motor protein that moves towards plus end of microtubules

Question 30

MAP

Answer 30

Microtubule associated protein

Question 31

Adherens junction

Answer 31

An adhesion complx connecting the actin cytoskeleton of adjoining epithelial cells via cadherins and catenins

Question 32

Connexin

Answer 32

Transmembrane protein that makes up a gap junction

Question 33

Connexon

Answer 33

Assembly of six connexins that makes up the gap junction channel on a cell

Question 34

Desmosome

Answer 34

Cell adhesion structure connecting the intermediate filaments of adjoining cells via cadherin like molecules

Question 35

Familial adenomatous polyposis

Answer 35

Inherited disorder characterized by large number of benign growths in the colon, caused by mutations in the APC gene

Question 36

Hemidesomosome

Answer 36

Cell adhesion structure connecting intermediate filaments of epithelial cells to the Extracellular Matrix

Question 37

Heterophilic binding

Answer 37

Binding of two cells to each other via different proteins

Question 38

Hemophiliac binding

Answer 38

Binding of two cells to each other via the same protein

Question 39

Selectin

Answer 39

Family of cell adhesion molecules that bind to sugar molecules

Question 40

Wnt

Answer 40

Wingless/integration protein; binding to its receptor causes B-catenin to accumulate inside cells