test 1: 1 failure of PT Flashcards
what is colostrum
1st milk produced after birth
large animal- yellow “liquid gold”
colostrum has a higher or lower amount of fat and protein than milk
higher
high potein from high IgG (antibodies) from mom
how can you improve colostrum made
- proper nutrition
- proper immunization/vaccines
high quality IgG should be > —
50 g/L
for cow
how does lactoferrin in colostrum work
binds to iron so bacteria can’t use it to multiply
way to prevent infection in young animal
what influences Ig content
▪ Maternal age and parity
▪ Breed
▪ Nutritional status
▪ Premature parturition
▪ Premature lactation (premilking)
▪ Time elapsed after parturition
▪ Mastitis
▪ Pooling
▪ Storage temperature
will a first time dam make better colostrum then a multiparous dam?
no
multi- better, can store and save to use for 1st time(primiparous) dam
placental classification for cow
cotyledonary
histo: epithelio-chorial
what affects antibody absorption
- age at 1st colostrum feeding
- mass of Ig fed
- method of feeding
how much colostrum does a cow need to get enough IgG
needs 200 g
if 50g/L
then needs 4 L or 1 gallon of good quality colostrum for enough IgG tranfer
8-10% of body weight
how to measure failure of passive transfer
expensive testing such as SRID, serym GGT or zinc sulfate turbidity
total protein on refractometor (blood from 3-7 day old calf)
Total protein valves for IgG levels in calf
use blood from 3-7 day old calf
TP < 5 is bad,
5-5.5 fair,
TP >5.5 adequate
IgG < 800 mg/dl bad,
IgG 800-1600 fair,
IgG >1600 adequate
how to treat failure of passive transfer in foals if colostrum not given in 24 hrs
plasma transfusion ($$)
bactermia vs sepsis
Bacteremia
– Bacteria in the bloodstream
Sepsis
– Clinical syndrome caused by bacteria and their toxins in
bloodstream which trigger a systemic inflammatory response that can cause damage to organs
portal of entry for sepsis in foal
umbilicus
GI tract
tonsils
prenatal: placentitis
