Terms Flashcards
Spread of cancerous cells via lymph and blood to sites far from original location
Metastatic carcinoma
Loss of cellular differentiation and function
Anaplasia
Indirect effects of cancers (ex: metabolism disturbances)
Paraneoplastic syndromes
Aggressive proliferation with tissue boundary breaches (especially basement membrane).
Invasive carcinoma
Genes that prevent malignancy. Both allele must be affected to see malignancy. Can be thought of as a loss of function alteration.
Tumor suppressor gene
Increase in size of tissue of organ due to increase in size of the component cells
Hypertrophy
Aggressive proliferation, but without invasion into basement membrane
Carcinoma in situ
Change of tissue from normal form to abnormal form
Metaplasia
Gene that can cause malignancy in a cell
Oncogene
New/abnormal formation of tissue (tumor or growth) with no useful function. (Neoplasia=growth, neoplasm=cells
Neoplasia/neoplasm
Abnormal development of tissue
Dysplasia