Terminal Respiration Flashcards
Where does it take place?
In the intermembrane space of the mitochondria. This is the only site of oxidative phosphorylation.
How is NADH from the cytoplasm transported to the mitochondrial matrix?
Through a glycerol phosphate shuttle. The cytosolic NADH can’t cross the membrane so it converts dihydroxyacetonephosphate to glycerol-3-phosphate which crosses the membrane and gives the elecrons to FAD.
This generates less ATP per mole than oxidation of NADH so there is a energy price.
What is the first complex called and what is it’s function?
NADH Q oxidoreductase oxidises NADH and passes the electrons to ubiquinone to give ubiquinol. It pumps protons into the intermembrane space. It uses an iron centre and flavin mononucleotide.
What is the second complex and what is it’s function?
It’s called succinate Q reductase and it oxidises FADH2 and passes the electrons on to ubiquinone. It also uses an iron centre to channel the electrons.
What is complex three called and what is it’s function?
It’s called cytochrome C oxidoreductase and it takes the electrons from ubiquinol and passes them to cytochrome C. It pumps protons into the intermembrane space.
What is the fourth complex and what is it’s function?
Its called cytochrome C oxidase and it takes the electrons from cytochrome C and passes them to O2. It pumps protons into the intermembrane space.
What is chemiosmosis?
As electrons pass through the different complexes protons move from the matrix to the intermembrane space.
What are the two parts of ATP synthase?
F0 which is a membrane bound protein conducting unit.
F1 protrudes into the mitochondrial matrix and acts as a catalyst for ATP synthesis.
How much energy is produced from the complete oxidation of glucose?
Either 30 or 32 dependant on the shuttle system
