Teratogenicity Flashcards
1
Q
Statins are contraindicated during pregnancy - true or false?
A
True - increased risk of congenital abnormality due to change in cholesterol synthesis
BNF recommends stop statins 3 months before trying to conceive
2
Q
Why is sitagliptin contraindicated in pregnancy and breastfeeding?
A
It is a DPP-4 inhibitor, so it inhibits an enzyme which acts on incretin
Incretin is a hormone that regulates insulin secretion
