Tentamen 5 Flashcards

1
Q

gevolgen van DNA breuken

A

translocaties
micronucleus

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2
Q

gevolg pyrimidine dimeer

A

puntmutatie

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3
Q

gevolgen verlies p53 gen

A

verminderde apoptose
defect in celcyclus checkpoint

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4
Q

wat doen metalloproteïnases

A

maken groeifactoren vrij en breken onoplosbare componenten af

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5
Q

skipmetastase

A

metastaseert zich in onverwachte klier

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6
Q

in transit metastase

A

kan tussen 2 lymfeklieren/stations gaan uitgroeien in lymfebaan

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7
Q

transcoelemische metastasering

A

gaat in lichaamsholte

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8
Q

disseminatie

A

term die wordt gebruikt voor metastasering bij lymfoïde / myeloïde tumoren

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9
Q

hoe kunnen tumorcellen uit tumoren komen

A

via efferente vaten en venules

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10
Q

wat is mesenchymale epitheliale transitie

A

migratie door bloedbaan en vervolgens uitgroei tot metastase

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11
Q

lead time

A

periode tussen preklinisch detecteerbaar worden en eerste klinische symptomen

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12
Q
A
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