Temolere

Question 1

Consists of?

Answer 1

Multiple repetitions of TTAGGG;

3’ overhang region

Question 2

How end replication problem arises?

Answer 2

Last primers removed by 5’->3’ exonuclease;

No DNA polymerase can fill the resulting gaps;

As no 3’OH available;

=> each round of replication generates shorter and shorter DNA molecule