tema 2 : eje hipotalamo-hipofisario GnRH + TSHRH Flashcards

1
Q

funcion de la GnRH

A

estimula produccion y liberacion FSH y LH

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2
Q

quien secreta la GnRH

A

la area preoptica

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3
Q

receptores de la GnRH

A

en la adenohipofisis

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4
Q

composicion de la GnRH

A

10 aminoacidos

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5
Q

mecanismo de accion de la GnRH

A

movilizacion del calcio intracelular

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6
Q

que facilita la liberacion de GnRH

A

los agonistas adrenergicos

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7
Q

que impide la liberacion de GnRH

A

los opiaceos

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8
Q

funcion de la TSHRH

A

liberadora de tirotropina y prolactina

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9
Q

composicion del TSHRH

A

tripeptidos con 3 aminoacidos

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10
Q

quien secreta la TSHRH

A

area hipotalamica anterior

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11
Q

mecanismo de accion de la TSHRH

A

aumento del calcio citoplasmatico

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11
Q

receptores de la TSHRH

A

celulas tiroideas

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12
Q

quien aumenta la respuesta de la FSHRH

A

los estrogenos

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13
Q

quien reduce la respuesta de la FSHRH

A

los androgenos

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14
Q

cual es son los factores liberadores de la Prolactina

A
  • neurotransmisores (serotonina, acetilcolina),
  • sustancias opiáceas
  • estrógenos.
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15
Q

cual es el principal factor hipotalamico

A

la dopamina con la actividad inhibidora de la liberacion de prolactina

16
Q

quien secreta la dopamina y la prolactina

A

el nucleo arcuato
el nucleo paraventricular

17
Q

mecanismo de accion de la dopamina

A

interaccionar con los receptores D2

18
Q

que inhibe la dopamina

A

formacion de AMPc y la síntesis de fosfoinositol

19
Q

que hormona inhibe la GH

A

la GHRIH o somatostatina

20
Q

composicion de la GHRIH

A

14 aminoacidos

21
Q

quien secreta la GHRIH

A

células específicas secretoras de somatostatina (células δ) de los islotes
pancreáticos.

22
Q

efectos de la GHRIH

A
  • regulacion de la insulina y del glucagon
23
Q

quien inhibe la secrecion de GH

A

la GHRIH