tema 2 : eje hipotalamo-hipofisario CRH + GHRH Flashcards

1
Q

de que esta lleno el hipotalamo

A

de nucleos

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2
Q

como la hipofisis anterior comunica con la adenohipofisis

A

con un sistema porta

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3
Q

hormonas hipotalamicas estimuladoras

A
  • CRH: hormona liberadora de corticotropina.
  • GHRH: hormona liberadora de la hormona de crecimiento.
  • GnRH o LHRH: hormona liberadora de gonadotropina.
  • TSHRH: hormona liberadora de tirotropina.
  • Factores liberadores de PRL: factores liberadores de prolactina.
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4
Q

funcion de la CRH

A

hormona liberadora de corticotropina ACTH

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5
Q

funcion de la GHRH

A

libera la hormona del crecimiento

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6
Q

funcion de la GnRH

A

libera gonadotropina

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7
Q

funcion de la TSHRH

A

libera tirotropina

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8
Q

composicion de la CRH

A

41 aminoacidos

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9
Q

quien secreta la CRH

A
  • neuronas hipotalamicas del nucleo paraventricular
  • nucleo supraoptico
  • nucleo arcuato
  • sistema limbico
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10
Q

receptores de las celulas corticotropicas

A

la adenohipofisis

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11
Q

mecanismo de accion de la CRH

A

aumento de AMPc

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12
Q

que disminuye la produccion de AMPc por la CRH ?

A

los glucocorticoides = cortisol

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13
Q

funcion de la GHRH

A

hormonadel crecimiento y produccion de GH

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14
Q

quien secretaa la GHRH

A

nucleo arcuato del hipotalamo

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15
Q

receptores de la GHRH

A

celulas hipofisarias

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16
Q

mecanismo de accion de la GHRH

A

activa la adenilciclasa
accumula AMPc

17
Q

que bloquea los efectos de la GHRH

A

la somatostatina

18
Q

que aumenta los efectos de la GHRH

A

los glucocorticoides