Telomers Flashcards
1
Q
Telomers are composed of what sequences
A
100-1000 copies of TTAGGG
2
Q
Chromosomes are shortened by about how many base pairs each time they are replicated
A
50
3
Q
How does telomerase work
A
Recognises the G rich telomere sequences on the 3’ overhang and extends it 5’ to 3’ one repeat unit at a time
4
Q
Telomerase does not do what
A
Fill in the gap opposite the 3’ end of the template strand, it extends the end 3’ of the template strand
5
Q
What is the unique Feature of telomerase
A
Built in mRNA template
6
Q
What happens once several telomere repeat units have been added
A
DNA polymerase catalyses the synthesis of the complementary strand
7
Q
Telomers are what
A
Non coding sequences at the ends of linear chromosomes
