TCA cycles and ETC Flashcards
1
Q
TCA cycle occurs on what part of mitochondria
A
mitochondrial matrix
2
Q
what cycles occur in the innermembrane space
A
ETC and ATP synthase
3
Q
can fatty acids be converted to acetyl CoA and back into sugars?
A
no
4
Q
what are the coenzymes and prosthetic groups for PDH
A
thiamine pyrophosphate lipoic acid CoA FAD NAD+
5
Q
Complex 1 of the ETC is known as
A
NADH dehydrogenase
6
Q
Complex 2 of the ETC is known as
A
succinate DH
7
Q
complex 3 of the ETC is known as
A
cytochrome b-c1 complex or ubiquinone cytochrome x reductase
8
Q
complex 4 of the ETC is known as
A
cytochrome oxidase
9
Q
what inhibits complex 1
A
barbituates “bacc”
10
Q
what inhibits complex 4
A
cyanide and carbon monoxide “bacc”
11
Q
what inhibits complex 3
A
antimycin “bacc”
12
Q
what inhibits coenzyme Q?
A
doxorubicin
13
Q
what are 3 examples of uncouplers
A
DNP, thermogenin, high dose asprin
