Tbl Flashcards
1
Q
- Which one of the below choices is not a complication of chronic gastritis?
A. Peptic ulcer disease
B. Squamous metaplasia
C. Mucosal atrophy
D. Intestinal metaplasia
E. Dysplasia
A
B. Squamous metaplasia
2
Q
- Which is the most common area for autoimmune gastritis?
* Proximal duodenum
* Gastro-esophageal junction
* Gastric cardia
D.
Neum
E. Gastric body
A
Gastric body
3
Q
- Which of the below choices is not associated with peptic ulcer disease?
A. Helicobacter pylori infection Alcohol ingestion
* Type A blood type
* Psychological stress
* Smoking
A
- Type A blood type
4
Q
- Which is the direct cause of increased acid secretion in peptic ulcer?
* H.pylori
* Local vasodilation
* Increased capillary permeability
* Formation & liberation of histamine
*. Stimulation of cholinergic intramural plexus
A
Formation & liberation of histamine
5
Q
- Which of the following is wrong about the comparison between gastric & duodenal ulcers?
* Serum pepsinogen level is increased in duodenal ulcer not in ulcer gastric
* Associated gastritis is seen in both forms Age of onset is higher in gastrie ulcer compared to duodenal Abnormal mucus is seen in both tvDes
E. Serum gastrin level is increased in gastric ulcer not in duodenal ulcer
A
Associated gastritis is seen in both forms
6
Q
- Which of the following drug group is used for acid peptic disease?
A. Corticosteroids
Anti-histaminic (H1 blockers) drugs
Ca Laxatives
D. Proton pomp inhibitors
E. SHT3 blockers
A
D. Proton pomp inhibitors
7
Q
Which of the following is not a H2- receptor antagonist
A. Ranitidine
B. Cimeudine
C. Famotidine
NizatKIine
Ampicilline
A
Ampicilline
8
Q
- Which of the following statements about cimetidine is wrong?
A. Not used for the treatment of gastroesophageal reflux disease . Available as oral and intravenous route
* Side effects include gynecomastia and galactornea
* Inhibits several cytochrome 1450 isoenzymes
B. Interfere with the metabolism ot many drugs
A
Not used for the treatment of gastroesophageal reflux disease
9
Q
- Which of the following is an analog of PGE1 that protects mucosa?
_Colloidal bismuth
* Misoprostol
* Sucralfate
* Metoclopramide
r. Ondansetron
A
Misoprostol
10
Q
- Which of the following pharmacodynamies and pharmacokinetic properties of proton pump inhibitors is wrong?
They are lipophilic weak bases
They diffuse into parietal cell canaliculi
Duration of action is 24 hours
* Reversibly inactivate the parietal cell HI’/ K* ATPase
* After absorption in intestine rapidly metabolized in liver (tin: 1-2 h)
A
- Reversibly inactivate the parietal cell HI’/ K* ATPase
11
Q
- Which of the following is a small molecule that polymerizes in stomach acid and coats the ulcer bed, resulling in accelerated healing and reduction of symptoms?
* Aluminum hydroxide
* Metoclopramide
* Sucralfate
* Dexamethasone
* MisoDrostol
A
Sucralfate
12
Q
- In addition to Helicobacter pylori infection of the stomach, what is the most common cause of peptic ulcer?
A. Use of nonsteroidal anti-inflammatory drugs (NSAIDs)
B.
Sternie
C. Smoking
D. AICOnO
Chaotress
A
Use of nonsteroidal anti-inflammatory drugs (NSAIDs)
13
Q
Which of the following is not a complication of P ulcer disease?
* Upper gastrointestinal bleeding
* Gastric outlet obstruction
* Perforation
* Hematuria
* Penetration
A
Hematuria
14
Q
- Which of the following is the most common type of peptic ulcer?
* Duodenal ulcers
* Gastric (stomach) ulcers
* Marginal ulcers
* Stress ulcers
* Curling ulcers
A
Duodenal ulcers
15
Q
- Which of the following conditions is the most feared result in parents with abers cansed by Helicobacter pylori?
A Gastrointestinal bleeding
B. Diabetes
C. Heart discase
D. Stomach cancer
E.
Gastric obstruction
A
Stomach cancer
16
Q
- Which of the following conditions is not alarm symptoms in patients with Puker disease?
A. Unintentional weight loss
B. Progressive dysphagia
C.
Nausea and vomiting
Recurrent and overt gastrointestinal bleeding
E. Iron deficiency anemia
A
Nausea and vomiting
17
Q
- A 30-year-old man presents to his physician with complaints of mid-epigastric pain. He describes the pain as moderate, occasionally waking him at night, and improving immediately following meals. A urease breath test was positive. Which of the following correctly describes the causal agent?
A. Cram-negative curved rod; microaerophilic
Gram-negative rod; aerobic
C. Gram-negative rod; lacultative anaerobe
Gram-positive rod; acrobic
E. Gram-positive rod: microaerophilic
A
A. Cram-negative curved rod; microaerophilic
18
Q
- A patient is admitted to the hospital because of a bleeding duodenal ulcer.
Culture at 37.0 C (98.6 F) reveals a urease-positive, gram-negative. curved rod. Which of the following is a likely complication due to infection with the causal agent?
A. Diarrhea
B. Kidney stones
C Pseudomembranous colitis
D. Stomach cancer
E. Vomiting
A
D. Stomach cancer
19
Q
- Which of the below choices is not a protective mechanism against mucosal injury in stomach?
* Mucin secreted by foveolar cells
* Presence of bicarbonate ions in mucin secreted by surface cells
* The rich blood supply to the mucosa
* Prèsence of serosal surface
* Neutral pH of mucin
A
Prèsence of serosal surface
20
Q
- What is the first morphologic change in gastritis?
* Macosal injury
* Plasma cell groups in lamina propria
C.
Shallow ulcers
* Reactive lymphoid hyperplasia
* Hemorrhage
A
Macosal injury
