Biochem Flashcards

1
Q

High serum lvl of alaine aminotranferase indicates only liver damage

A

F

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2
Q

Aminotranferase reactions are irreversible

A

F

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3
Q

Aminotranferase requires pyrodoxal phosphate a co factor derived from B6

A

True

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4
Q

Co factor of aminotranferase is attached to the enzyme via amide bond

A

F

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5
Q

Glutamine is the most common product of aminotranferase reactions

A

F

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6
Q

Choose amino acid used for protein synthesis but can’t be for humans except by metabolism of another amino acid which is impossible in normal metabolitoes

A

Tyrosine and cysteine

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7
Q

2 nitrogens in urea enter urea synthesis pathway in what molecular form

A

One as amonia and one as alpha amino group of aspartate

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8
Q

Person with phenylketonuria consumes food with high phenylalanine leads to

A

Phenylpyruvate

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9
Q

Oxidation of fatty acids is highest between meals and lower in well fed states

A

True

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10
Q

What is bilirubin conjugated with in jaundice

A

Glucuronic acid

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11
Q

Carbs are beneficial because food with sugar tastes better

A

F

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12
Q

Carbs are required for fat oxidation

A

F

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13
Q

Carbs prevent hypoglycemia

A

T

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14
Q

Carbs improve renal functions

A

F

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15
Q

Carbs improve urea synthesis in the liver

A

F

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16
Q

Nitric oxide and urea have in common this amino a id which is used as an immediate precursor

A

Arginine

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17
Q

Which of the following incorrectly pairs a pathway with one of it’s regulated enzymes

A

Urea cycle carbamoyl phosphate synthetase ll CPS II

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18
Q

Glucogenesis: which of the following incorrectly pairs a glycotic enzyme with the glucogenic enzyme that catalizes the reverse

A

Pyruvate kinase pyruvate dehydrogenase (turns pyruvate to acetylcoa)

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19
Q

Which one is the precursor of potent vasoconstrictor serotonin

A

Tryptophan

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20
Q

Which of the following essential dietary factors is a precursor for a compound as a carrier of the acetate group (two-carbon fragment)?
A. Methionine
B. Thiamine
C. Folic acid
D. Biotin
E. Pryidoxine

A

Thiamine

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21
Q

Choose the wrong statement in the transamination of amino acids.
A. Pyridoxal phosphate is a cofactor
(B) The reaction is tightly controlled by allosterie effectors
© The amino group acceptor is typically an a-keto acid alpha keto glutarate
D. Ammonia is neither consumed nor produced
E. Proline is one of few amino acids which are not subjected to transamination

A

(B) The reaction is tightly controlled by allosterie effectors

22
Q

Which one of the following amine acids is purely Ketogenic regarding the fate of carbon skeletons?
A. Isoleucine
B. Tyrosine
C. Alanine
D.Leucine
E. Gycine

A

(D? Leucine

23
Q
  1. Choose the wrong statement regarding the digestion of proteins?
    A. Pepsinogen is activated by autoactivation (pH 2) or autocatalysis
    B. The major products of peptic hydrolysis are mostly large peptides
    C. Trypsin and chymotrypsin are secreted by the pancreas as inactive zymogens
    D. Enteropeptidase (enterokinase) activates pancreatic trypsinogen
    dipeptides / small
    Most of the digested proteins are absorbed in the intestines in the form of polypeptides
A

Most of the digested proteins are absorbed in the intestines in the form of polypeptides

24
Q

Which enzymatic activity in the pentose phosphate pathway requires thiamine pyrophosphate (TPP) as a cofactor?
A. Glucose 6-phophate dehydrogenase (G6PD)
B. 6-Phosphogluconate dehydrogenase
C.Transketolase
D. Transaldolase
E. Phosphopentose isomerase

A

Transketolase

25
Q

Which polysaccharide cannot be hydrolysed by humans due to the presence ofthep finkage in repeating units?

A. Amylopectin
B. cellulose
D. Starch
E. Glycogen

A

Cellulose

26
Q

A protein X is formed by two chains with 80 amino acids in one chain and 58 in the other.
These two chains are linked by disulfide bonds and all the essential amino acids are present in the structure. but not all the non-essential amino acids. With this information, how can you classify this protein according to the nutritional value?
A. A globular protein
B. A fibrous protein
C. A conjugated protein
D. An incomplete protein
E.A complete protein

A

(E) A complete protein

27
Q
  1. An amino acid that yieldsfacetoacetyl Co/ during the catabolism of its carbon skeleton would be considered as one of the following. Choose the correct answer.
    A. Glycogenic
    B. Ketogenic
    C. Glycogenic and ketogenic
    D. Neither glycogenic nor ketogenic
    E. Essential
A

Ketogenic

28
Q

ketogenic and glucogenic that yield acetoacety

A

tryptophan, phenylalanine, tyrosine

29
Q
  1. Which carriers are used to transport the NH, produced in muscle degradation of nitrogenated compounds through blood to the liver?
    A. Alanine and glutamine
    B. Urea and alanine
    C. NH: and glutamate
    D. Glutamate and glutamine
    E. a-Ketoglutarate and urea
A

Alanine and glutamine

30
Q
  1. Choose the correct answer for the necessary coenzyme for transmination reactions
    A.Prridoxal phosphate
    B. Thiamine pyrophosphate
    C.Coenzyme A
    D. Tetrahydrobiopterin
    E. Folate
A

Prridoxal phosphate

31
Q

Amino acids are requared for the syntheses of other nitrogen compoundse

A

T

32
Q

Essential amino scads must be obtained in the diet daily.

A

T

33
Q

Nitrogen is continuously lost from the body regard less of the protein intake amount

A

T

34
Q

…. proteins have the highest biological value

A

Animal origin

35
Q

Protein degradation to provide energy results in

A

Loss of other functions

36
Q

The carbon atoms of serine can, appear in all of the following except one of them. Indicate which ore is that?
A. Pyruvite
B.leucine
C.glycine
D.sphyngomylin
Ephosphatidyl ethanolamine

A

sphyngomylin

37
Q

Which of the following is an intermediate in the degradation of lysine?

A

Seccharopine

38
Q

All amino acids are glucogenic.

A

F

39
Q

Amino acid catabolisen is increased during…

A

Starvation

40
Q

All amino acids are essential amino acids.

A

F

41
Q

The major excrctory end profact of acmino acid catabolism is

A

Urea

42
Q

Tissue proccin synthesis is decreased duting periods of growth.

A

F

43
Q

Besides diet restrictions, bat warranting an apocopriate amount of the essential amine aids, which of the following amino acids you should supelement in higher quantities than in a normal dict. since it is essential for a PRU (obenytectonuna) patient.

A

Tyrosine

44
Q

The diet must supply only enough phenylalanine and
tyrosine to meet the needs for

A

protein synthesis.

45
Q

Which of the following is an example of the oxidative desination reaction taking part in amino acids metabolism

A

Glutamate = alpha-Ketoglunarate + NH3

46
Q

Glutamate=hexanoic acid+NH3

A

Glutamate dehydrogenase

47
Q

Pepsinogen us activated by

A

Auto activated ph2
Autocatalysis

48
Q

Major products of peptiv hydrolysis

A

Large peptides

49
Q

Trypsin amd chemotrypsin are secreted by… as…

A

Pancreas
Inactive zygomens

50
Q

Enterokinase activates

A

Pancreatic trypsinogen

51
Q

….. is an amino acid not subjectted to transmination

A

Proline