TB Drugs

Question 1

Isoniazid (INH, Nytrazid) Uses

Answer 1

active TB
latent TB (+TB skin test, disease not yet active)
treatment is 6-9 months

Question 2

Isoniazid side effects

Answer 2

GI S/S (N, V, Constipation)
Liver dmg or failure (common in older adults and ETOHers)
peripheral neuropathy
CNS S/S (dizzy, ataxia, seizures, psychotic symptoms)

Question 3

Isoniazid interventions

Answer 3

monitor and report GI symptoms
encourage compliance with drug regimen
monitor liver enzyme levels
report signs of liver dmg
administer B6 for neuropathy

Question 4

Rifampin uses

Answer 4

given in conjunction with Isoniazid
orally or IV
1 hr before or 2 hours after meal
absorption is decreased with food
decreases blood levels of oral contraceptives, warfarin.

Question 5

Rifampin side effects

Answer 5

GI S/S
Liver toxicity
red-orange color of body fluids (urine, saliva, tears, sweat)

Question 6

Rifampin interventions

Answer 6

monitor liver enzymes
report S/S of hepatitis
monitor for discoloration of body fluids
monitor and report GI symptoms