ABX that attack the cell wall Flashcards
ABX that interfere with cell wall synthesis
PNCN Cephalosporins Monobactams Carbapenems Vancomycin
penicillin: amoxicillin (Amoxil)
amoxicillin + clavulanic acid (Augmentin)
Side affects
N, V, D
suprainfection (C. Diff, candida albicans)
allergy (rash, hives)
anaphylaxis
penicillin: amoxicillin (Amoxil)
amoxicillin + clavulanic acid (Augmentin)
interventions
monitor for GI symptoms
report bloody stools or watery diarrhea
monitor for allergic rxn
report candida infections of mouth or vagina
cephalosporin: cephalexin (Keflex)
side effects
N, V, D
risk of hemorrhage
thrombophlebitis
disulfiram like rxn when taken with ETOH (flushing, tachycardia, N, thirst, chest pain, vertigo, hypotension)
cephalosporin: cephalexin (Keflex)
interventions
monitor for GI symptoms prepare to treat for allergic rxn monitor PT and INR monitor for thrombopheblitis monitor renal function inform PT about disulfiram like rxn
monobactam: aztreonam (Azactam)
side effects
thrombophlebitis
suprainfection
monobactam: aztreonam (Azactam)
interventions
monitor IV site
monitor for candida
frequent hydration for mouth pain
carbapenem: imipenem and cilastatin (Primaxin)
meropenem (Merrem )
side effects
N, V, if ivp is done too rapidly
thrombophlebitis
suprainfection
carbapenem: imipenem and cilastatin (Primaxin)
meropenem (Merrem )
interventions
follow recommended rate for infusion
monitor for N during infusion
monitor IV site
monitor for infection
vancomycin side effects
hypotension flushing of face and trunk hearing loss due to ototxicity kidney dmg thrombophlebitis
vancomycin interventions
monitor vitals
monitor for hearing loss
monitor lab work
monitor iv site