ABX that attack the cell wall Flashcards

1
Q

ABX that interfere with cell wall synthesis

A
PNCN
Cephalosporins
Monobactams
Carbapenems
Vancomycin
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2
Q

penicillin: amoxicillin (Amoxil)
amoxicillin + clavulanic acid (Augmentin)
Side affects

A

N, V, D
suprainfection (C. Diff, candida albicans)
allergy (rash, hives)
anaphylaxis

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3
Q

penicillin: amoxicillin (Amoxil)
amoxicillin + clavulanic acid (Augmentin)
interventions

A

monitor for GI symptoms
report bloody stools or watery diarrhea
monitor for allergic rxn
report candida infections of mouth or vagina

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4
Q

cephalosporin: cephalexin (Keflex)

side effects

A

N, V, D
risk of hemorrhage
thrombophlebitis
disulfiram like rxn when taken with ETOH (flushing, tachycardia, N, thirst, chest pain, vertigo, hypotension)

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5
Q

cephalosporin: cephalexin (Keflex)

interventions

A
monitor for GI symptoms
prepare to treat for allergic rxn
monitor PT and INR
monitor for thrombopheblitis
monitor renal function
inform PT about disulfiram like rxn
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6
Q

monobactam: aztreonam (Azactam)

side effects

A

thrombophlebitis

suprainfection

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7
Q

monobactam: aztreonam (Azactam)

interventions

A

monitor IV site
monitor for candida
frequent hydration for mouth pain

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8
Q

carbapenem: imipenem and cilastatin (Primaxin)
meropenem (Merrem )
side effects

A

N, V, if ivp is done too rapidly
thrombophlebitis
suprainfection

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9
Q

carbapenem: imipenem and cilastatin (Primaxin)
meropenem (Merrem )
interventions

A

follow recommended rate for infusion
monitor for N during infusion
monitor IV site
monitor for infection

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10
Q

vancomycin side effects

A
hypotension
flushing of face and trunk
hearing loss due to ototxicity
kidney dmg
thrombophlebitis
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11
Q

vancomycin interventions

A

monitor vitals
monitor for hearing loss
monitor lab work
monitor iv site

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