TB Flashcards
1
Q
What causes TB?
A
- M. tuberculosis
* M. bovis
2
Q
What is the pathology of TB?
A
Primary infection
- Localised lung lesion
- Heals with development of specific immunity
- Asymptomatic in 90% of patients
- Can be haematogenous spread
Post-primary disease
- Reactivaton of persisting mycobacteria
- Much greater immune response
- Usually symptomatic
3
Q
What is active TB?
A
- Containment by the immune system is inadequate
- Can arise from primary infection or latent infection
4
Q
What is latent TB?
A
- Infection without disease due to immune system containment -> granuloma formation - Contains bacterial growth and spread
5
Q
What are the systemic symptoms of TB?
A
- Weight loss
- Night sweats
- Anorexia
- Fevers
6
Q
What are the pulmonary symptoms of TB?
A
- Cough +/- sputum
- Haemoptysis
7
Q
What are the lymph node symptoms of TB?
A
- Painless lymphadenopathy
- Node is firm and not acutely inflamed
8
Q
What are the pleuritic symptoms of TB?
A
Pleuritic pain
9
Q
What are the bone symptoms of TB?
A
- Progressive bone/joint pain
- Swelling
10
Q
What are the GI symptoms of TB?
A
- Colicky abdominal/pelvic pain
- Constipation
- Vomiting
- Bowel obstruction (bowel wall thickening)
11
Q
What are the genitourinary symptoms of TB?
A
- Sterile pyuria (white cells in urine and absence of bacteria)
- Dysuria
- Frequency
- Loin pain
- Haematuria
- Strictures
- Infertility
- Gential ulceratiob
12
Q
What are the CNS symptoms of TB?
A
- Headache
- Vomiting
- Irritability
- Confusion
- CN abnormalities
- Meningitis
13
Q
What are the cardiac symptoms of TB?
A
- Pericarditis
- Pericardial effusion +/- constrictive pericarditis
14
Q
What are the skin symptoms of TB?
A
- Erythema nodosum
- Lupus vulgaris
15
Q
What would a CXR show in primary disease?
A
- Primary focus
