TB Flashcards
1
Q
TB - investigations
A
sputum samples
CXR
HIV test - immunosuppression can reactivate latent TB
2
Q
primary TB - what is it?
A
exposed to m.tb → may develop primary infection of lungs → small lung lesion (Ghon focus) develops - made of tubercle-laden macrophages
immunocompotent people: lesion usually heals by fibrosis
immunocompromised: may develop disseminated disease (miliary tb)
3
Q
secondary TB - what is it?
A
host becomes immunocompromised → reactivation in apex of lungs → may spread locally or distally
4
Q
extra-pulmonary TB - sites?
A
CNS - tb meningitis - most serious complication vertebral bodies - Pott's disease cervical LNs - scrofuloderma kidneys GI tract
