TB Flashcards
Primary TB
silent usually contained and 98% contained
Lymphatic dissemination
reactivation TB
symptomatic
usually pulmonary but may attack other organs
occurs months to decades after primary disease
TB in bone
Pott’s disease
most people who have had primary TB usually
don’t even know they had it
how does secondary TB travel?
hematogenous dissemination durring reactivation of a (ghon) focus established durring the primary infection
when does secondary TB occur?
months, years, decades or never after primary disease.
what contributes to dissemination?
density of organisms in environment and sputa
extent of disease and vaccination
upper airlways lesions
velocity and expired air
viscosity of sputum
frequency of coughing and sneezing
drugs
Clinical manifestation of primary pulmonary TB
mostly silent or minimal:cough,wt.loss, perspiration, anorexia, dyspnea, occasional chest pain
children most likely to have symptoms
10% of children have erythema nodosum(sarcoid too)
no clinical evidence infection in ___ of patients. ___ of adults have primary TB
98%
15% (yocum says 10-12%)
Big Orange first hits
Hilary lymph
___% of children ____% of adults have lymphadenopathy
90%
40%
Primary manifestations of primary poulonary tb
Parenchymal infiltrates
hilary lymphadenopathy
ghon tubercle
calcified parenchymal nodule
ranke complex
Histo:geographic
TB(called ghon)
coccydio:geographic
Post primary TB can be _____
anywhere
