Target Volumes (for all sites)

Question 1

Target volumes for cervix brachy:

What do you prescribe to:

Typical boost dose

Answer 1

GTVbrachy = Macroscopic tumour extension at the time of brachytherapy as detected by clinical examination and MRI imaging.

High risk CTVbrachy = GTVbrachy + whole cervix and the presumed extra cervical extension at the time of brachytherapy as detected by clinical examination and MRI imaging.

Intermediate risk CTVbrachy
HR CTVbrachy + safety margin of 0.5 -1.5cm.

D90 High risk CTVbrachy = HR-CTVbrachy (D90)

Typical boost dose = 24/3 (up to 30/5) 1-2 depending on timing of brachytherapy in relation to EBRT. Delivered 1-3 days apart.

Question 2

Volume, dose and chemo for definitive cervix EBRT:

Answer 2

45/25 (50.5/28), 1.8Gy/#, 5#/week