TACE Flashcards
What is TACE
Transarterial
Chemoembolization
places chemotherapy and synthetic materials called embolic agents into a blood vessel feeding a cancerous tumor to cut off the tumor’s blood supply and trap the chemotherapy within the tumor
TACE
carries blood to the liver from the intestines, spleen, pancreas, and gallbladder
Hepatic Portal Vein
Give 5 clinical indications of TACE
- Unresectable hepatocellular carcinoma
- Selective Metastatic disease
- Cholangiocarcinoma
- decreasing liver function
- patient’s daily activity performance capabilities
- lack of microvascular invasion
- limited extrahepatic disease
- isolated or hepatic dominant metastatic deposits
give 5 contraindications of TACE
- Extensive tumor infiltration throughout the liver
- Encephalopathy
- Large burden of extra-hepatic metastases
- Liver or renal failure
- Uncorrectable coagulopathy
- Acute Decompensation of baseline liver function
- Iodinated contrast allergies
- Portal Vein Thrombosis
This condition refers to low levels of red blood cells, white blood cells or platelets
Sever cytopenia
What do you call the condition that refers to low levels of RBC?
Anemia
What do you call the condition that refers to low levels of WBC?
Leukopenia
What do you call the condition that refers to low levels of platelets?
Thrombocytopenia
approaches of TACE
Trans-femoral route (hepatic artery approach)
What is the chemotherapy drug used in TACE?
doxorubicin 50 mg, cisplatin 100 mg, 10 ml iodinated non-ionic CM, 20 ml liopodol
Give 5 complications of TACE
Generalized abdominal discomfort
Low-grade fever
Nausea
Malaise
Hepatic Insufficiency
Abscess
Biliary necrosis
Tumor rupture
Cholecystitis
Aftercare of TACE
- Daily Monitoring of liver and renal function
- Follow-up imaging at 3-16 weeks
- Inspection of pseudo-
aneurysms
Procedure of Tace
- make a small incision on the femoral artery
- insert catheter through incision
- using real time fluoro, guide catheter to tumor
- Inject die through the catheter to make it easier to visualise the tumor
- Inject chemotherapy drug to tumor
- Remove catheter, put bandage over incision