tables from sanders (cell signaling) Flashcards
epinephrine (adrenaline)
receptor = GPCR
g-protein coupled receptor
cortisol hormone
intracellular receptor
estradiol hormone
intracellular receptor
glucagon hormone
GPCR
growth hormone
tyrosine kinase-associated receptor
Insulin (hormone)
Receptor Tyrosine Kinase
Testosterone
Intracellular receptor
Thyroid hormone/T3/Thyroxine
intracellular receptor
Vitamin D3
intracellular receptor
Epidermal Growth Factor (EGF)
Receptor tyrosine kinase (RTK)
platelet-derived growth factor (PDGF)
receptor tyrosine kinase (RTK)
Nerve growth factor (NGF)
Receptor tyrosine kinase (RTK)
Transforming growth factor-B
Serine/threonine receptor kinase
Nitric oxide (NO)
permanently binds guanylyl cyclase
Acetylcholine (ACh)
GPCR
Hormones that act on GPCRs
- Epinephrine
- glucagon
- Acetylcholine
Hormones that bind to intracellular receptors
- cortisol
- estradiol
- testosterone
- Thyroid hormone (T3/Thyroxine)
- Vitamin D3
hormones that bind to RTKs (receptor tyrosine kinases)
- insulin
- EGF (epidermal growth factor)
- PDGF (platelet-derived GF)
- NGF (nerve GF)
G alpha S and I proteins
Effector: adenylyl cyclase 2nd mess: cAMP (S - up, I- down) Receptors: S - beta Adrenergic, glucagon, serotonin, vasopressin Rs I - alpha adrenergic, Ach Rs
G olf alpha protein
effector: AC
2nd mess: cAMP (up)
Receptor: odorant Rs
G q and o alpha protein
effector: PLC
2nd mess: IP3, DAG
Receptor: Ach (o)
G t protein
effector: cGMP phosphodiesterase
2nd mess: cGMP (down)
Receptor: rhodopsin
