tables from sanders (cell signaling) Flashcards

1
Q

epinephrine (adrenaline)

A

receptor = GPCR

g-protein coupled receptor

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2
Q

cortisol hormone

A

intracellular receptor

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3
Q

estradiol hormone

A

intracellular receptor

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4
Q

glucagon hormone

A

GPCR

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5
Q

growth hormone

A

tyrosine kinase-associated receptor

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6
Q

Insulin (hormone)

A

Receptor Tyrosine Kinase

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7
Q

Testosterone

A

Intracellular receptor

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8
Q

Thyroid hormone/T3/Thyroxine

A

intracellular receptor

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9
Q

Vitamin D3

A

intracellular receptor

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10
Q

Epidermal Growth Factor (EGF)

A

Receptor tyrosine kinase (RTK)

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11
Q

platelet-derived growth factor (PDGF)

A

receptor tyrosine kinase (RTK)

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12
Q

Nerve growth factor (NGF)

A

Receptor tyrosine kinase (RTK)

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13
Q

Transforming growth factor-B

A

Serine/threonine receptor kinase

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14
Q

Nitric oxide (NO)

A

permanently binds guanylyl cyclase

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15
Q

Acetylcholine (ACh)

A

GPCR

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16
Q

Hormones that act on GPCRs

A
  • Epinephrine
  • glucagon
  • Acetylcholine
17
Q

Hormones that bind to intracellular receptors

A
  • cortisol
  • estradiol
  • testosterone
  • Thyroid hormone (T3/Thyroxine)
  • Vitamin D3
18
Q

hormones that bind to RTKs (receptor tyrosine kinases)

A
  • insulin
  • EGF (epidermal growth factor)
  • PDGF (platelet-derived GF)
  • NGF (nerve GF)
19
Q

G alpha S and I proteins

A
Effector: adenylyl cyclase
2nd mess: cAMP (S - up, I- down)
Receptors: 
S - beta Adrenergic, glucagon, serotonin, vasopressin Rs
I - alpha adrenergic, Ach Rs
20
Q

G olf alpha protein

A

effector: AC
2nd mess: cAMP (up)
Receptor: odorant Rs

21
Q

G q and o alpha protein

A

effector: PLC
2nd mess: IP3, DAG
Receptor: Ach (o)

22
Q

G t protein

A

effector: cGMP phosphodiesterase
2nd mess: cGMP (down)
Receptor: rhodopsin