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Prudent use of Antimicrobials > Table- entrance > Flashcards

Table- entrance Flashcards

1
Q

Penicillins- Narrow spectrum

A

benzylpenicillin- Na, K
benzylpenicillin-benzathine
phenoxymethyl-penicillin

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2
Q

Penicillins-Penicillinase stable

A

oxacillin
cloxacillin
diclocloxacillin
flucloxacillin

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3
Q

Penicillins- broad spectrum

A

amoxicillin

ampicillin

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4
Q

Penicillins- Pseudomonas acting

A

ticarcillin

piperacilin

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5
Q

Penicillins: mode of action and mechanism of action

A

Time dependent Bactericidal

Inhibit cell wall synthesis

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6
Q

Beta lactamase inhibitors

A

Clavulinic acid
Sulbactam
Tazobactam

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7
Q

Cephalosporins: 1st generation

A

Cephazoline
Cephapirin
Cephalexin
Cefadroxil

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8
Q

Cephalosporin: 2nd generation

A

Cefuroxime

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9
Q

Cephalosporin: 3rd generation

A 
Ceftiofur
Cefovecin
Cefotaxime
Ceftazidime
Cefoperazone
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10
Q

Cephalosporin: 4th generation

A

Cefquinome

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11
Q

Cephalosporines: mode of action and mechanism of action

A

Time dependent Bactericidal

Inhibit cell wall synthesis

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12
Q

Carbapenams

A

imipenem

meropenem

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13
Q

Carbapenams: mode of action and mechanism of action

A

Time dependent Bactericidal

Inhibit cell wall synthesis

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14
Q

Monobactams

A

Aztreonan

Tigemonam

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15
Q

Monobactams: mode of action and mechanism of action

A

Time dependent Bactericidal

Inhibit cell wall synthesis

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16
Q

Beta lactams antibiotics

A 
Penicillins
beta lactamase inhibitors
cephalosporines
carbapenams
monobactams
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17
Q

Aminoglycosides

A 
Streptomycin
Neomycin
Paromycin
Kanamycin
Gentamycin
Tobramycin
Amikacin
Apramycin
Spectinomycin (bacteriostatic)
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18
Q

Aminoglycoside: mode of action

A

Conc. Dependent bactericidal (except spectinomycin which is bacteriostatic)

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19
Q

Aminoglycoside: mechanism of action

A

Inhibit protein synthesis (30s subunit), mistranslation

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20
Q

Tetracyclines: Short acting

A

Chlorotetracycline
Oxytetracycline
Tetracycline

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21
Q

Tetracyclines: long acting

A

Doxycycline

Minocycline

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22
Q

Tetracyclines: mode of action

A

Bacteriostatic

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23
Q

Tetracyclines: mechanism of action

A

Inhibit protein synthesis (30s subunit)

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24
Q

Macrolides

A 
Erythromycin
Azithromycin
Clarithromycin
Spiramycin
Tylosin
Tylvalosin
Tilmicosin
Tulathromycin
Gamithromycin
Tildipirosin
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25
Q

Macrolides: mode of action

A

Bacteriostatic

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26
Q

Macrolides: mechanism of action

A

Inhibition of protein synthesis (50s subunit)

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27
Q

Lincosamides

A

Lincomycin

Clindamycin

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28
Q

Lincosamides: mode of action

A

Bacteriostatic

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29
Q

Lincosamides: Mechanism of action

A

Inhibition of protein synthesis (50s subunit)

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30
Q

Pleuromutilins

A

Tiamulin

Valnemulin

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31
Q

Pleuromutilins: mode of action

A

Bacteriostatic

32
Q

Pleuromutilins: mechanism of action

A

Inhibition of protein synthesis (50s subunit)

33
Q

Phenicols

A

Chloramphenicol
Florfenicol
Thiamphenicol

34
Q

Phenicol: mode of action

A

Bacteriostatic

35
Q

Phenicol: mechanism of action

A

Inhibition of protein synthesis (50s subunit)

36
Q

Peptide AB: Polypeptide

A

Bacitracin
Polymxin B
Polymyxin E= colistin

37
Q

Peptide: Glycopeptide AB

A

Vancomycin

Teicoplanin

38
Q

Peptide AB: Polypeptide: mode of action

A

Conc. dependent, Bactericidal

39
Q

Peptide AB: Polypeptide: mechanism of action

A

They act like a cationic detergent

40
Q

Peptide: Glycopeptide AB: mode of action

A

Time dependent, bactericidal

41
Q

Peptide: Glycopeptide AB: mechanism of action

A

Inhibit cell wall synthesis

42
Q

Rifamycins

A

Rifampicin

43
Q

Rifamycin: mode of action

A

time dependent, bactericidal

44
Q

rifamycin: mechanism of action

A

inhibit bacterial DNA- dependent RNA polymerase

45
Q

Pseudomonic acid

A

Mupirocin

46
Q

Pseudomonic acid: mode of action

A

bactericidal

47
Q

Pseudomonic acid: mechanism of action

A

inhibit cell wall synthesis

48
Q

Phosphoric acid

A

Fosfomycin

49
Q

Phosphoric acid: mode of action

A

Bactericidal

50
Q

Phosphoric acid: mechanism of action

A

Inhibit cell wall synthesis

51
Q

Fusidic acid

A

fusidic acid

52
Q

Fusidic acid: mode of action

A

Bacteriostatic

53
Q

Fusidic acid: mechanism of action

A

Inhibit protein synthesis

54
Q

Sulphonamides

A 
Sulfadimidine
Sulfadiazine
Sulfachlorpyrazine
Sulfachlorpyrdazine
Sulfamethoxasole
Sulfadoxine
Sulfaquinoxaline
Sulfasalazine
55
Q

Sulphonamide: mode of action

A

Separately bacteriostatic and when combined time dependent bactericidal

56
Q

Sulphonamide: mechanism of action

A

Inhibition of folic acid synthesis (PABA)

57
Q

Diaminopyrimidines

A

Trimethoprim

Baquiloprim

58
Q

Diaminopyrimidines: mode of action

A

Separately bacteriostatic and when combined time dependent bactericidal

59
Q

Diaminopyrimidines: mechanism of action

A

Inhibition of folic acid synthesis (PABA)

60
Q

Fluoroquinolines: 1st generation

A

Nalidixic acid

61
Q

Fluoroquinolines: 2nd generation

A 
Fumequin
Norflaxacin
Orbifloxacin
Ciprofloxacin
Enrofloxacin
Danofloxacin
Diflofloxacin
Marbofloxacin
62
Q

Fluorquinolines: 3rd generation

A

Levofloxacin

Sparofloxacin

63
Q

Fluoroquinolines: 4th generation

A

Pradofloxacin

Moxifloxacin

64
Q

Fluorquinolin: mode of action

A

Conc. dependent Bactericidal

65
Q

Fluoroquinoline: mechanism of action

A

Inhibit DNA synthesis

66
Q

Nitrfurans

A

Nitrofurantoin

Furazolidine

67
Q

Nitrofuran: mode of action

A

Bactericidal

68
Q

Nitrofurans: mechanism of action

A

Destroy DNA of bacteria

69
Q

Nitrimidazoles

A

Metronidazole
Ronidazole
Tinidaazole

70
Q

Nitroimidazoles: mode of action

A

Conc. dependent Bactericidal

71
Q

Nitroimidazoles: Mechanism of action

A

Destroy DNA of bacteria

72
Q

Conc. dep. Bactericidal

A

Fluoroquinolines
Polypeptides
Colistin
Aminoglycosides (spectinomycin:bacteriostatic)

73
Q

Time dep. Bactericidal

A 
Penicillin
Cephalosporin
carbapenams
monobactams
glycopeptide
Potentiated sulphonamide
Rifamycines
74
Q

Bacteriostatic

A 
Tetracycline
macrolide
phenicols
lincosamides
pleuromutilins
fusidic acid
sulphonamides+diaminopyrimidine when alone
75
Q

Beta lactamase group

A

Penicillins
Beta-lactamase inhibitors

Cephalosporins
carbapenems
Monobactams

Prudent use of Antimicrobials (4 decks)

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