Table 4 - Anti-Arrhythmics Flashcards
Naturally occurring nucleoside
Adenosine
Decreases myocardial excitability and conduction velocity; may depress contractility (by increasing electrical threshold)
Procainamide
For life-threatening ventricular arrhythmias
Procainamide
Electrolyte
MgSO4 (IV)
Inhibits adrenergic alpha and beta stimulation affecting Na, K, and Ca channels; prolongs AP and refractory period; decreases AV conduction and sinus node function
Amiodarone
Class 3 repolarization delay via K channels
Amiodarone
Slows conduction in cardiac tissue (by altering transport of ions across cell membranes), causes slightly prolonged refractory periods, increases threshold
Flecainide
Adrenergic B1 and B2 receptor inhibitor; reduces O2 demand, HR, contractility, BP
Propranolol
Class 1C Na channel blocker
Flecainide
Class 4 calcium channel: CCB NDHP
Verapamil, Cardizem
Dilates coronary arteries and decreases O2 demands
Verapamil, Cardizem
PSVT: Slows conduction time through AV node by interrupting reentry pathways in AV node and restoring NSR
Stress testing: Causes coronary vasodilation and increases blood flow in normal coronary arteries with little to no increase in stenotic coronary arteries
Adenosine
Inhibits Na/K pump causing increased Ca influx causing increased contractility; decreases ventricular rate (by suppressing AV node)
Digoxin
Selective B1 adrenergic receptor inhibitor
Metoprolol and Atenolol
Class 1A Na channel blocker
Procainamide