Table 2 - Antihypertensives

Question 1

Renin-angiotensin inhibitors: ACEI

Answer 1

Captopril, Lisinopril, Fosinopril

Question 2

NaCl symporter inhibition in the DCT increasing Na and Cl excretion max 5% of filtered NaCl

Answer 2

HCTZ, Chlorthalidone

Question 3

Alpha-1 Blockers

Answer 3

Prazosin

Question 4

Vasodilators: Direct acting

Answer 4

Hydralazine

Question 5

Diuretics: “Thiazide-Like”

Answer 5

Chlorthalidone

Question 6

Direct acting arteriolar vasodilator

Answer 6

Hydralazine

Question 7

Angiotensin Receptor blockers: ARBs

Answer 7

Losartan

Question 7

Direct renin inhibitor

Answer 7

Aliskirin

Question 9

B1, B2, A1 blockers

Answer 9

Carvedilol

Question 11

Vasodilators: DHP CCB

Answer 11

Amlodipine, Nifedipine

Question 12

Direct adjunct: K+ Sparing

Answer 12

Triamterine

Question 13

Loop diuretic

Answer 13

Furosemide, Turosemide, Edecrin

Question 14

Adrenergic B1 and B2 receptor inhibitor, reduction in myocardial oxygen demand

Answer 14

Propranolol (NON SELECTIVE B-BLOCKER)

Question 15

Vasodilators: NDHP CCB

Answer 15

Cardizem, Verapamil

Question 16

Selective B1 adrenergic receptor inhibitor

Answer 16

Metoprolol tartrate/succinate, Atenolol

Question 17

Selective alpha-1 blocker which relaxes smooth muscle in arteries, veins, and the prostate

Answer 17

Prazosin

Question 18

Centrally acting A2 adrenergic agonist

Answer 18

Clonidine, Methyldopa

Question 19

Mixed alpha and beta receptor inhibition

Answer 19

Carvedilol

Question 20

SURPRISE Which beta blocker can be used in heart failure?

Answer 20

Carvedilol

Question 21

Direct inhibitor of Na+ influx in DCT and CCT

Answer 21

Triamterene

Question 22

Inhibits Na+-K+-2Cl- symporter in TAL of loop and distal tubule

Answer 22

Furosemide

Question 23

Stimulates alpha 2 receptors in the brain stem which stimulates an inhibitory neuron resulting in reduced sympathetic outflow from CNS which results in a reduction in TPR

Answer 23

Clonidine

Question 24

Central alpha-adrenergic inhibition decreases sympathetic outflow to heart, kidneys, and peripheral vasculature

Answer 24

Methyldopa

Question 25

Selectively and competitively blocks AT 1 (1000X greater) and AT 2 receptors

Answer 25

Losartan

Question 26

Direct renin inhibitor preventing conversion of antiotensinogen to angiotensin I (AT1) which reduces conversion to angiotensin II (AT2) producing arteriolar vasodilation

Answer 26

Aliskirin

Question 29

Dilate coronary arteries and decrease myocardial oxygen demans

Answer 29

Cardizem, verapamil

Question 30

Sympatholytics: Peripheral Adrenergic “R” Blockers - Beta blockers

Answer 30

Propranolol, Metoprolol Tartrate/Succinate, Atenolol

Question 30

Diuretics: Thiazides

Answer 30

Hydrochlorathiazide

Question 30

Competitive inhibitor of ACE preventing conversion angiotensin I to angiotensin II decreasing vasoconstriction by angiotensin II and decreases aldosterone secretion

Answer 30

Captopril, Lisinopril, Fosinopril

Question 30

Vasodilation due to blocking calcium channels in vascular smooth muscle and myocardium

Answer 30

Amlodipine, Nifedipine