Table 2 - Antihypertensives Flashcards

1
Q

Renin-angiotensin inhibitors: ACEI

A

Captopril, Lisinopril, Fosinopril

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2
Q

NaCl symporter inhibition in the DCT increasing Na and Cl excretion max 5% of filtered NaCl

A

HCTZ, Chlorthalidone

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3
Q

Alpha-1 Blockers

A

Prazosin

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4
Q

Vasodilators: Direct acting

A

Hydralazine

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5
Q

Diuretics: “Thiazide-Like”

A

Chlorthalidone

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6
Q

Direct acting arteriolar vasodilator

A

Hydralazine

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7
Q

Angiotensin Receptor blockers: ARBs

A

Losartan

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7
Q

Direct renin inhibitor

A

Aliskirin

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9
Q

B1, B2, A1 blockers

A

Carvedilol

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11
Q

Vasodilators: DHP CCB

A

Amlodipine, Nifedipine

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12
Q

Direct adjunct: K+ Sparing

A

Triamterine

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13
Q

Loop diuretic

A

Furosemide, Turosemide, Edecrin

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14
Q

Adrenergic B1 and B2 receptor inhibitor, reduction in myocardial oxygen demand

A

Propranolol (NON SELECTIVE B-BLOCKER)

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15
Q

Vasodilators: NDHP CCB

A

Cardizem, Verapamil

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16
Q

Selective B1 adrenergic receptor inhibitor

A

Metoprolol tartrate/succinate, Atenolol

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17
Q

Selective alpha-1 blocker which relaxes smooth muscle in arteries, veins, and the prostate

A

Prazosin

18
Q

Centrally acting A2 adrenergic agonist

A

Clonidine, Methyldopa

19
Q

Mixed alpha and beta receptor inhibition

A

Carvedilol

20
Q

SURPRISE Which beta blocker can be used in heart failure?

A

Carvedilol

21
Q

Direct inhibitor of Na+ influx in DCT and CCT

A

Triamterene

22
Q

Inhibits Na+-K+-2Cl- symporter in TAL of loop and distal tubule

A

Furosemide

23
Q

Stimulates alpha 2 receptors in the brain stem which stimulates an inhibitory neuron resulting in reduced sympathetic outflow from CNS which results in a reduction in TPR

A

Clonidine

24
Q

Central alpha-adrenergic inhibition decreases sympathetic outflow to heart, kidneys, and peripheral vasculature

A

Methyldopa

25
Q

Selectively and competitively blocks AT 1 (1000X greater) and AT 2 receptors

A

Losartan

26
Q

Direct renin inhibitor preventing conversion of antiotensinogen to angiotensin I (AT1) which reduces conversion to angiotensin II (AT2) producing arteriolar vasodilation

A

Aliskirin

29
Q

Dilate coronary arteries and decrease myocardial oxygen demans

A

Cardizem, verapamil

30
Q

Sympatholytics: Peripheral Adrenergic “R” Blockers - Beta blockers

A

Propranolol, Metoprolol Tartrate/Succinate, Atenolol

30
Q

Diuretics: Thiazides

A

Hydrochlorathiazide

30
Q

Competitive inhibitor of ACE preventing conversion angiotensin I to angiotensin II decreasing vasoconstriction by angiotensin II and decreases aldosterone secretion

A

Captopril, Lisinopril, Fosinopril

30
Q

Vasodilation due to blocking calcium channels in vascular smooth muscle and myocardium

A

Amlodipine, Nifedipine