Table 3 - Anti-Lipid Agents

Question 1

HMG-CoA reductase inhibitors

Answer 1

If it ends in “statin” it does this

Atorvastatin, etc.

Question 2

Bile-acid sequestrants

Answer 2

Cholesytramine, Colesevelam

Question 3

Fibric acids

Answer 3

Fenofibrate, Gemfibrazil

Question 4

Nicotinic acid Vitamin B3

Answer 4

Niacin

Question 5

Cholesterol absorption inhibitor

Answer 5

Exetimibe

Question 6

Other - LOL

Answer 6

Omega 3 fatty acids

Question 7

PCSK9 inhibitor

Answer 7

Evolocumab

Question 8

Inhibits cholesterol synthesis

Answer 8

Statins

Question 9

Binds bile acids inhibiting enterohepatic circulation of cholesterol

Answer 9

Cholestryamine, Colesevelam

Question 10

Not known; theories on changes in various enzymes involved in VLDL and IDL metabolism

Answer 10

Gemfibrozil, fenofibrate

Question 11

Inhibits fatty acid release from adipose tissue and hepatic trig production

Answer 11

Niacin

Question 12

Decreases absorption of cholesterol from GI tract

Answer 12

Exetimibe

Question 13

Human monoclonal antibody that binds to proportion converts subtilisin kexin type 9 (PCSK9) inhibiting the degradation of LDLR - This decreases the number of LDLR’s available to clear LDL from blood, thereby lowering LDL-C levels

Answer 13

Evolocumab