T3 - Probs of PNS (Josh) Flashcards
Guillian Barre is a problem of the —
PNS
Guillian Barre is caused by what?
demylenation of peripheral nerves which leads to disruption of sensory and motor pathways
Etiology of Guillian Barre
Immune mediated response (IgG antibodies)
Viral Infections
Bacterial Infections
Vaccines
Lymphoma
Surgery
Trauma
Patho of Guillian Barre
T cells migrate to peripheral nerves
Macrophages break down myelin
Inflammation can cause axonal damage (mostly temporary)
What are the stages of Guillian Barre?
Initial (1-4 wks)
Plateau (several days to 2 yrs)
Recovery (4-6 mths up to 2 yrs)
S/S of Guillian Barre
Initial muscle weakness and pain
ASCENDING paralysis
Autonomic dysfunction
Motor weakness
Cranial nerve dysfunction
Resp dysfunction
Guillian Barre:
What is the Ascending paralysis?
symmetric, bilateral, ascending motor loss
Guillian Barre:
What is the Autonomic Dysfunction caused by GB?
BP fluctuations
Dysrhythmias
Guilliian Barre:
Which cranial nerves are typically affected?
III: Occulomotor
VII: Facial
IX: Glossopharyngeal
X: Vagus
XI: Accessory
XII: Hypoglossal
Guillian Barre:
What happens to respiratory function?
changes in Tidal Volume
Treatment plan of Guililan Barre:
Plasmapheresis
Intravenous Immune Globulin (IVIG)
Guillian Barre:
What is Plasmapheresis?
removes circulating antibodies assumed to cause the disease
Plasma is selectively separated from whole blood
Plasma usually replaces itself or is transfused with albumin
Guillian Barre:
What is the treatment regimen if the use IVIG?
daily dose based on body weight for 5 consecutive days
Nursing care for Guillian Barre.
Treat the symptoms
Monitor for complications
Early Mobility
Enteral Feedings
Guillian Barre:
What are the cardio complications?
Acute Dysautonomia (HR, BP)
Guillian Barre:
What are the things we need to monitor for with respiratory care?
Atelectasis
VAP
Pneumothorax
ARDS
Guillian Barre:
What are the GI complications we need to monitor for?
decreased motility (paralytic ileus)
- **give Reglin
- **listen to bowel sounds
- **keep up with BMs
— — is an autoimmune disease characterized by muscle weakness.
Myasthenia Gravia
What is Myasthenia Gravis caused by?
antibodies interfere with the transmission of ACh at the neuromuscular junction
What are the different types of Myasthenia Gravis?
Occular
Generalized
What is Tensilon Testing?
baseline assessment of cranial muscle strength
**tested with Myasthenia Gravis
What is a positive Tensilon Test?
onset of muscle tone improvement within 30-60 secs after Tensilon injection
***lasts 4-5 mins