T2DM Flashcards
1
Q
What percentage of diabetic have Type 2?
A
90%
2
Q
Which cells secrete insulin & glucagon?
A
Islets of Langerhans
Alpha cells = glucagon
Beta cells = insulin
3
Q
What is the biochemical action of insulin?
A
In adipose & muscle cells - binds to insulin receptor to stimulate uptake of glucose transporters to cell membranes (reduces glucose in blood)
4
Q
What is the biochemical action of glucagon?
A
Induces gluconeogenesis & glycolysis in the liver (to increase blood glucose)
5
Q
What percentage of the world population have diabetes?
A
10%
6
Q
What are the 4 hallmark symptoms of diabetes?
A
Polyuria & glycosuria
Polydipsia
Polyphagia
7
Q
MODY
A
Mature onset of diabetes of the young
