T2: Pulmonary System (2) Flashcards
When does shunting occur?
when a portion of the VENOUS blood does not participate in gas exchange
Examples of conditions that may cause anatomic shunting:
- AVMs
- ARDS
- atelectasis
- pneumonia
- pulmonary edema
- pulmonary embolus
- vascular lung tumors
- intracardiac R to L shunt
Does increased FiO2 help when shunting occurs?
No
Does PCO2 change or stay the same when shunting occurs? Why?
stays the same
B/c compensation with increased RR
Venous blood that flows through the lungs w/o being oxygenated due to nonfunctioning alveoli:
intrapulmonary shunting
Intrapulmonary shunting:
____% is abnormal
____% is life-threatening
greater than 10% = abnormal
greater than 30% = life-threatening
What 2 methods can be used to measure shunting?
- Direct measurement
- Estimation
How do we directly measure shunting?
- Give 100% O2 for 15 min
- measure CaO2 and CvO2
CaO2 means ____.
CvO2 means ____.
CaO2 = O2 content of arterial blood CvO2 = O2 content of venous blood
CaO2 - CvO2 normal is ____ ml/dl.
5 ml/dl
How do we estimate shunting?
- PaO2 / PAO2 ratio
- Alveolar-arterial gradient
- PaO2 / FiO2 ratio
What is the A-a gradient?
The alveolar (PAO2) to arterial (PaO2) pressure difference
PAO2 means ____ pressure
PaO2 means ____ pressure
PAO2 = alveolar O2 pressure PaO2 = arterial O2 pressure
Why is the A-a gradient always positive?
You always have more O2 in the lungs than in the body tissue
What is a normal A-a gradient?
10-20 mmHg
increases within this range as the pt ages
What does A-a gradient show?
How efficiently the lung is managing pulmonary capillary O2 and alveolar O2
If the A-a gradient is large, this indicates a dysfunction in the ___.
lung
(it’s not picking up the O2 like it should
Issues that can lead to large A-a gradient:
- V/Q mismatching
- shunting
- diffusion abnormalities
What is the formula to find PAO2?
PAO2 = FiO2 (PB - PH2O) - PaCO2 / RQ
Abbreviation for fraction of inspired oxygen:
FiO2
Abbreviation for barometric pressure. What is normal?
PB
760 mmHg
Abbreviation for pressure of water vapor. What is normal?
PH2O
47 mmHg