T2 L18:Lower Limb Nerve Injuries and Compartment Syndrome Flashcards

1
Q

what is the difference between a Cauda equina vs conus lesion

A

1)The conus medullaris is the terminal end of the spinal cord, which typically occurs at the L1 vertebral level in the average adult.[1] Conus medullaris syndrome (CMS) results when there is compressive damage to the spinal cord from T12-L2

The cauda equina is a group of nerves and nerve roots stemming from the distal end of the spinal cord, typically levels L1-L5 and contains axons of nerves that give both motor and sensory innervation to the legs, bladder, anus, and perineum.[2] Cauda equina syndrome (CES) results from compression and disruption of the function of these nerves and can be inclusive of the conus medullaris or distal to it, and most often occurs when damage occurs to the L3-L5 nerve roots

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2
Q

where is lumbar puncture performed

A

it is performed between L3 and L4

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3
Q

name some differences between cauda equina lesions and conus medullaris

A

Pain severity in cauda equina is radicular and more severe

location of pain in cauda equina is unilateral/asymmetric in the perineum, thighs and legs but in the Conus medullaris it is bilateral in the perineum and thighs

sensory disturbance in the cauda equina is saddle and unilateral but in Conus medullaris its bilateral saddle distribution

reflexes in the cauda equina that are affected are ankle and knee but in Conus medullaris ankle only is reduced

bowel/bladder in cauda equina is late but in Conus medullaris its early

sexual function in the cauda equina is impaired ad less severe but in Conus medullaris it’s impaired and more severe

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4
Q

what are causes of lesions in the cauda equina

A

Disc herniation, spinal fracture and tumours

in the Conus medullaris : -disc herniation, tumour and inflammatory conditions- ie- Chronic Inflammatory Demyelinating Polyradiculopathy • Sarcoidosis

also infection- CMV, HSV, EBV, Lyme, TB

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5
Q

give a common area of herniation casing compression of cauda equina

A

L5/S1 herniation

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6
Q

describe nerve entrapment Sciatica

A

Compression- Disc- posterior central, lateral Bone- osteophyte Ligaments Small canal- stenosis

Sciatica – usually L5, S1 n. root impingement

L5 n. root – exits between L5/ S1 vertebral bodies S1 n. root exits between S1 / S2 vertebral bodies

Pain may be felt in dermatome (sharp/ superficial) or myotome (deep ache)

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7
Q

describe the lower limb dermatomes

A

L1 inguinal area L2 front of thigh (front pocket) L3 front of knee L4 front- inner/ medial leg L5 outer leg, dorsum of foot, inner sole S1 little toe, rest of sole, back of leg S2 thigh to top of buttock (back pocket) S3-S5 concentric rings round anus/ genitalia

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8
Q

describe the dermatomic reflexes

A

Knee jerk L4 Ankle jerk S1

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9
Q

describe where the lower limb root lesions occur and their corresponding weaknesses

A

L1/2 Hip flexion

L3/4 Knee extension L4 Foot inversion

L5 Knee flexion Ankle dorsiflexion Toe extension Foot inversion and eversion

S1 Knee flexion Ankle plantar flexion Toe flexion Foot eversion

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10
Q

go over lumbar and sacral plexus

A

how was it

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11
Q

describe the aetiology of Lumbosacral Plexus Lesions

A

Childbirth (large head, prolonged labour)- esp obturator n., numbness inner thigh, pudendal n. 

 Structural
 – Haematoma (on Warfarin)
 – Abscess 
– Malignancy
 – infiltration
 – Trauma  
Non structural 
 – Inflammatory, 
 – Diabetes
 – Vasculitis
 – Radiotherapy
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12
Q

describe ow lesions affect femoral nerve organisation

A

Hip flexors, Iliopsoas affected if proximal damage (above inguinal Ligament)
Only knee extension if below inguinal ligament
Distal lesion may produce a pure motor or pure sensory syndrome

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13
Q

describe femoral/lateral cutaneous nerve damage and pic

A

Femoral N. Weakness Hip flexion (iliacus) Knee Extension Loss of Knee Jerk Can’t do stairs

Sensory loss Lat Cut. N. Thigh (relief if seated)

Sensory loss Femoral N.

Difficulty standing from seated Up stairs, knee buckling

Saphenous (sensory branch of femoral n.)

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14
Q

describe the surgical procedures that lead to Femoral nerve injury

A

Gynae procedures, esp hysterectomy, femoral a. bypass/ puncture)

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15
Q

describe the aetiology of sciatica

A

Pain in sciatic n. distrib

Nerve root entrapment (usually L5 / S1)

Differential diagnosis: Hip – pain may radiate not below knee Sacroiliac joints

Causes: Trauma, Haematoma Rarely sciatic nerve compression per se (Piriformis synd) Or misplaced IM injections

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16
Q

what is piriformis syndrome

A

Controversial as to whether muscle compression per se can cause tingling in buttock and down leg (eg after exercise or straining, or prolonged sitting)

Probably may rarely occur in those with anatomical predisposition.

No consensus on criteria Diagnosis of exclusion

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17
Q

what occurs in sciatic nerve injury

A

Apart from Hip flexion Knee extension Hip adduction

Sciatic nerve or its branches, are motor to virtually all other muscle groups in the leg

Isolated Hip fracture – sciatic n. Pelvic/ sacral fracture – sacral plexus)

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18
Q

2 compartments of sciatic nerves

A

Beware Partial sciatic n. damage can look like Common peroneal or Tibial n. damage

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19
Q

look over major divisions of sciatic nerves

A

how was it

20
Q

describe the tibial nerve -behind knee lesions

A

Can’t stand on tiptoes Weak foot inversion Painful numb sole

Causes: Trauma: Haemorrhage Bakers cyst Nerve tumour Entrapment by the tendinous arch at the soleus muscle.

21
Q

what muscles are effected by tibial nerve injury

A
  • tibialis posterior
  • Flexor digitorum longus
  • Flexor hallucis longus

Intrinsic foot muscles

Sole pain worse standing/ walking Not heel pain Differential Morton’s neuroma

22
Q

describe sural nerve location

A

how was it

23
Q

describe the effects of lesions to the common peroneal nerve

A

May also be damaged by tight plaster casts, leg crossing, Weight loss- slimmers palsy

Sensory loss -dorsum of foot and outer aspect lower leg

Weakness of -dorsiflexion and eversion of foot

24
Q

describe the neurogenic foot drop

A

Upper motor neuron
(brain/ spinal cord)

 Conus 
L4/L5 
Cauda equina  Sacral plexus  Sciatic n.
Common peroneal n.

25
Q

describe Polyneuropathy

A

– generalised relatively homogeneous process affecting many peripheral nerves with the distal nerves affected most prominently. 

26
Q

describe peripheral neuropathy

A

refers to any disorder of the peripheral nervous system including radiculopathies and mononeuropathies

27
Q

describe length dependent polyneuropathy

A
Common causes (Toxic/metabolic)
 – Diabetes
 – Alcohol 
– B12 def 
– Chemotherapy
 – Idiopathic  

Clinical symptoms – Numbness, paraesthesia, weakness
– Pain

28
Q

describe the non-length dependent polyneuropathy

A

Guillain Barre syndrome :

Also known as Acute inflammatory demyelinating polyneuropathy

 Immune response to a preceding infection 

Rapidly progressive (days to weeks) weakness including limbs, facial, respiratory and bulbar muscles

 Absent reflexes

29
Q

describe neuronopathy

A

 Form of polyneuropathy 

Disorders that affect specifically population of neurons.

 Motor neuronopathy

– Site of damage: Anterior horn cell
– Causes: ALS, Polio 
Sensory neuronopathy
– Site of damage : Doral root ganglion

– Causes: Sjogrens syndrome, Paraneoplastic

30
Q

describe neuronopathy

A

Site of damage to cause sensory neuronopathy - dorsal root ganglion

Site of damage to cause motor neuronopathy -motor neuron in spine

31
Q

describe polyradiculopathy

A

Affects multiple nerve roots.  Causes:
– Spinal stenosis: Cervical, lumbar
– Cancer: Leptomeningeal metastases
– Infection: Lyme, HIV,

32
Q

Types of peripheral neuropathies

A

neuronopathy

polyneuropathy

poly(radiculopathy)

33
Q

describe shin splints

A

Muscle bulk increases 20% during exercise and contributes to the transient increase in intracompartmental pressure

Anterior and lateral compartments of the lower leg are commonly affected Generally causes pain on and post exercise- AKA Shin Splints

Manage with RICE (rest / cooling – ice)

34
Q

describe compartment syndrome

A

Increase in pressure within a myofascial compartment which has limited ability to expand

May be acute or chronic

Acute compartment syndrome is a surgical emergency

35
Q

where does compartment syndrome (CS) occur

A

Any limb compartment Commonest Lower leg Forearm

Also Hand Foot

leg in particular

36
Q

what causes CS

A
Fractures (1-6% Tibial Fractures
 Crush Injuries
 Burns 
Electric Shock
 Fluid Injection 

Drugs • Warfarin/other anticoagulants • Anabolic Steroid use • Iv drug use

Disease • Haemophilia

External Causes • Tight splints/casts • Tourniquet

37
Q

what are the consequences of CS-physiology

A

Tissue perfusion is proportional to the difference between the capillary perfusion pressure and the interstitial fluid pressure

elevated compartment pressure causes muscle and nerve ischemia

38
Q

Consequence of CS - pathology

A

Untreated, within 6-10 hours, the final result is muscle infarction, tissue necrosis, and nerve injury

Certain tissues are more sensitive than others and this can be a clue to diagnosis Sensory nerves

39
Q

what is injured in Acute anterior CS leg

A

Dorsiflexion muscles of ankle and foot :Tibialis anterior, Extensor digitorum longus Extensor hallucis longus, Peroneus tertius

Anterior tibial artery: Commonly injured in lateral tibial plateau fractures

Deep peroneal nerve: Sensation to the first dorsal web space

40
Q

where does acute posterior CS occur in the leg

A

Superficial posterior :

Plantar flexors of foot

  • Gastrocnemius -Plantaris 
  • Soleus

Sural nerve -Sensation to lateral aspect of the foot and distal calf

41
Q

what are the signs of acute posterior CS leg

A

 Pain! (out of proportion to the original injury) 

Pain +++ on passive stretching

 Tense limb

 Decreased function of the compartment muscles

 Distal neurologic compromise 

Reduced distal pulses

42
Q

what investigations can be done for CS

A

Clinical suspicion is all important

Measuring of intra-compartmental pressures can be useful

Creatine kinase (CK) of 1000-5000 U/mL

Myoglobinuria

43
Q

management of acute CS

A

Genuine confirmed CS is an emergency

Often surgery is required Aim is to lay open the myofascial compartment and diminish intra-compartmental pressure

However don’t forget to look for external causes

  • Tight casts/ splints
  • Dressings
44
Q

how does Treatment of compartment synd

A

fasciotomy procedure- incision in skin and fascia to release pressure

vessels are no longer compressed; capillaries are functional

45
Q

what are the Complications of mismanagement of CS

A

If fasciotomy is performed within 25-30 hours following onset of acute CS, the prognosis is good Little or no return of function can be expected when diagnosis and treatment are delayed

Rhabdomyolysis - Renal Failure

Limb Loss