T1DM

Question 1

What is T1DM?

Answer 1

T1DM is characterised by an autoimmune condition in which pancreatic beta-cells of the Islets of Langerhans are dysfunctional. Partial or complete deficiency of insulin production > Hyperglycaemia
Resultant hyperglycaemia > Chronic insulin treatment.

Question 2

What is LADA?

Answer 2

Autoimmune diabetes leading to insulin deficiency can present later in life = latent autoimmune diabetes in adults (LADA).

Question 3

Can diabetic ketoacidosis be a feature of T2DM?

Answer 3

Yes; presents in childhood

Question 4

T1DM is though to be a condition of childhood and dearly adulthood. Keeping this in mind what is the challenge caused by this fact.

Answer 4

Difficult to differentiate between adult-onset type I diabetes from type II diabetes.

Question 5

Is T1DM associated with a genetic predisposition that is potentiated by an environmental trigger?

Answer 5

Yes