T1-Drugs

Question 1

Acetylcholine

Answer 1

cholinergic agonist- muscarinic miosis(pupil constriction) during surgery

Question 2

carbachol

Answer 2

cholinergic agonist- muscarinicmiosis(pupil constriction) during surgery

Question 3

bethanechol

Answer 3

cholinergic agonist- muscarinic. improve poor bladder tone and increase GI motility

Question 4

methacholine

Answer 4

cholinergic agonist- muscarinic. used for asthma test

Question 5

pilocarpine

Answer 5

cholinergic agonist- muscarinic. reduce IOP in open angle glaucoma

Question 6

cevimeline

Answer 6

cholinergic agonist- muscarinic. dry mouth

Question 7

chantix

Answer 7

cholinergic agonist- nicotinic. stop smoking

Question 8

atropine

Answer 8

selective muscarinic antagonist: mydriases(dilate iris) and thicken lens.

• decrease mucosal secretion
• increase BP
• increase HR
• overactive bladder
• muscarinic agent or cholinesterase inhibitor poisoning treatment

Question 9

hyoscyamine

Answer 9

selective muscarinic antagonist

Question 10

ipratropium

Answer 10

selective muscarinic antagonist: bronchodilation in asthma

Question 11

tiotropium (spiriva)

Answer 11

selective muscarinic antagonist:

Question 12

tolterodine (detrol)

Answer 12

selective muscarinic antagonist: urinary urgency

Question 13

oxybutynin

Answer 13

selective muscarinic antagonist: urinary urgency

Question 14

solifenacin (vesicare)

Answer 14

selective muscarinic antagonist: urinary urgency

Question 15

benztropine (cogentin)

Answer 15

selective muscarinic antagonist: parkinsons

Question 16

scopolamine

Answer 16

selective muscarinic antagonist:

Question 17

glycopyrrolate

Answer 17

selective muscarinic antagonist

Question 18

darifenacin (enablex)

Answer 18

selective muscarinic antagonist

Question 19

cyclopentolate

Answer 19

selective muscarinic antagonist

Question 20

amitriptyline

Answer 20

nonselective muscarinic antagonist

Question 21

dicyclomine

Answer 21

nonselective muscarinic antagonist

Question 22

benadryl

Answer 22

nonselective muscarinic antagonist

Question 23

ambenonium

Answer 23

cholinesterase inhibitor

Question 24

demecarium

Answer 24

cholinesterase inhibitor

Question 25

donepezil

Answer 25

cholinesterase inhibitor

Question 26

echothiophate

Answer 26

irreversible cholinesterase inhibitor. treats glaucoma

Question 27

galantamine

Answer 27

cholinesterase inhibitor

Question 28

malathione

Answer 28

irreversible cholinesterase inhibitor

Question 29

DFP

Answer 29

irreversible cholinesterase inhibitor for glaucoma

Question 30

neostigmine

Answer 30

semi reversible cholinesterase inhibitor for glaucoma, and MG therapy

Question 31

physostigmine

Answer 31

reversible cholinesterase inhibitor for glaucoma and atropine toxicity

Question 32

pyridostigmine

Answer 32

semi reversible cholinesterase inhibitor for MG

Question 33

rivastigmine (exelon)

Answer 33

cholinesterase inhibitor

Question 34

tacrine

Answer 34

cholinesterase inhibitor

Question 35

edrophonium (tensilon)

Answer 35

reversible cholinesterase inhibitor for diagnosing and dose assessment of MG

Question 36

soman

Answer 36

irreversible cholinesterase inhibitor

Question 37

tabun

Answer 37

irreversible cholinesterase inhibitor

Question 38

pralidoxime (2-PAM)

Answer 38

cholinesterase regenerator

Question 39

atracurium

Answer 39

non depolarizing nicotinic antagonist

Question 40

doxacurium

Answer 40

non depolarizing nicotinic antagonist

Question 41

mivacurium

Answer 41

non depolarizing nicotinic antagonist

Question 42

pancuronium

Answer 42

non depolarizing nicotinic antagonist

Question 43

rocuronium

Answer 43

non depolarizing nicotinic antagonist

Question 44

tubocurarine

Answer 44

non depolarizing nicotinic antagonist

Question 45

dantrolene

Answer 45

non depolarizing nicotinic antagonist

Question 46

d-tubocurarine

Answer 46

non depolarizing nicotinic antagonist

Question 47

vencuronium

Answer 47

non depolarizing nicotinic antagonist

Question 48

succinylcholine

Answer 48

depolarizing nicotinic antagonist

Question 49

decamethonium

Answer 49

depolarizing nicotinic antagonist

Question 50

general receptor effects of cholinergic agonist

Answer 50

• decrease HR and BP
• increase GI motility
• pupil constriction
• increase secretion
• bronchial constriction

Question 51

general receptor effects muscarinic antagonists :CNS

Answer 51

-increase vagal nerve activity

Question 52

general receptor effects muscarinic antagonist: cardio

Answer 52

• decrease HR initially b/c of vagal nerve stimulation. eventually blocking of M2 receptors cause an increase in BP

Question 53

general receptor effects muscarinic antagonist: respiratory

Answer 53

-bronchodilation

Question 54

general receptor effects muscarinic antagonist: GI

Answer 54

• decrease in:

salivation, gastric secretion, and GI motility

Question 55

general receptor effects muscarinic antagonist: urinary

Answer 55

urine retention (relaxed ureter and bladder smooth muscle)

Question 56

general receptor effects muscarinic antagonist: sweating

Answer 56

atropine fever

Question 57

general receptor effects cholinesterase

Answer 57

• decrease HR
• decrease BP
• increase Gi motility
• pupil constriction
• increase then decrease in IOP
• increase in secretions
• bronchial constriction

Question 58

general receptor effects depolarizing nicotinic antagonist

Answer 58

• activation receptors to cause Na influx, causing partial depolarization and contraction.
• when Ach activates the receptor further, flaccid paralysis can occur
• the partially depolarized motor end plate results in inactive nicotinic channels and Ach cannot repolarize

Question 59

general receptor effects non depolarizing nicotinic antagonist

Answer 59

• 2 Ach binds to nicotinic receptor to activate. if 1 is antagonist, the activity is decreased
• can be reversed by cholinesterase inhibitors