T-Cells

Question 1

What is another name for T-Cells?

Answer 1

TLymphocytes

Question 2

Where do they mature?

Answer 2

Thymus gland

Question 3

What do they respond too?

Answer 3

Antigens presented on body cells

Own cells altered by viruses/cancer to transplanted tissues

Question 4

How do TCells are able to distinguish difference between these cells and own cells? (4)

Answer 4

1. Phagocytes that have engulfed &hydrolysed a pathogen present some of the pathogens antigens on their surface
2. Body cells invaded by a virus present viral antigens on their surface - distress signals
3. Cancer cells are different from normal cells and present them on their surface
4. Transplanted cells from the same species have different antigens on their cell surface

Question 5

What are antigen-presenting cells?

Answer 5

Cells that display foreign antigens are known as antigen-presenting cells

Question 6

What do the receptors respond to?

Answer 6

The receptors on each Tcell respond to a single antigen. There are a huge number of different TCells that each respond to a different antigen

Question 7

What is a Cytotoxic TCell?

Answer 7

Tc cells attack abnormal body cells. Produce a protein molecule called perforin the makes holes in the the cell-surface membrane. This makes the cell freely permeable killing it. This action is very affective against viruses as they replicate inside the cells