T細胞 Flashcards

1
Q

活化的毒殺型T細胞可分泌那些物質促進目標細胞凋亡

A

Perforin
Granzymes
Granulysin
FAS-FASL

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2
Q

Th cell可分成

A

Th1、Th2、Th17、Treg

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3
Q

上皮內淋巴細胞可分成哪兩群細胞

A

CD8 alpha:beta T cell

CD8 alpha:alpha T cell

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4
Q

CD8 alpha:beta T cell功能

A

清除胞內感染的目標細胞

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5
Q

CD8 alpha:alpha T cell功能

A

產生記憶型CD8+ T cell

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6
Q

IL-1的分泌細胞及其功能

A

抗原呈現細胞

使被活化的輔助型T細胞產生IL-2

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7
Q

IL-2功能

A

使T細胞增生(生成許多Th0)

增加Tc細胞毒殺力

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8
Q

Th0可分化成哪些細胞

A

Th1
Th2
Th17
Treg

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9
Q

巨噬細胞分泌哪一細胞激素可促進Th1的生成

A

IL-12

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10
Q

哪一細胞激素可促進Th2的生成

A

IL-4

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11
Q

巨噬細胞分泌哪一細胞激素可促進Th17的生成

A

IL-6

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12
Q

哪一細胞激素可促進Treg的生成

A

TGF-beta

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13
Q

Th1會產生哪些細胞激素

A

IFN-gamma
IL-2
IL-3, GM-CSF

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14
Q

Th2會產生哪些細胞激素

A

IL-3, GM-CSF
IL-4, IL-6
IL-5
IL-10

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15
Q

當抗原為細菌、病毒時,輔助型T細胞會分化成

A

Th1

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16
Q

當抗原為過敏原、寄生蟲時,輔助型T細胞會分化成

A

Th2

17
Q

IFN-gamma功能

A

增加巨噬細胞吞噬力

抑制Th2生成

18
Q

IL-3, GM-CSF功能

A

增加巨噬細胞的數量

19
Q

IL-4, IL-6功能

A

增加B細胞的數量

20
Q

IL-5功能

A

增加嗜酸性白血球的數量

21
Q

IL-10功能

A

抑制Th1生成

22
Q

TFH1和TFH2可藉由何種機制造成 isotype switch

A

CD40-CD40L

23
Q

IL-17功能

A

促進嗜中性球的作用

24
Q

Treg功能

A

在無感染時,抑制Th1, Th2…的作用

25
Q

治療過敏需要給予哪些細胞激素

A

IFN-gamma

IL-12

26
Q

哪些細胞激素是抑制型的

A

IFN-gamma
IL-10
TGF-beta

27
Q

哪些細胞激素Th1, Th2皆會分泌

A

IL-3, GM-CSF

28
Q

超級抗原定義

A

能自發結合到TCR的V beta和MHC2的分子(不需MHC呈現)