Systems Review 2: CNS, ENT, Orthopedics, Obstetrics Flashcards
Percentage of Brain, Blood and CSF?
Normal ICP?
Brain 80%
Blood 12%
CSF 8%
Normal ICP: <15 mmHg (Pressure in brain is too much for blood flow from heart)
Avg. adult brain weighs _____g
O2 consumption is 20% of total body consumption, or ______ml/g/min
1400g (2% of body weight)
- 3ml/100g/min
- 50ml/min total
Normal cerebral blood flow?
Normal: 50 ml/100 Gm/min
15% of cardiac output
As long as the cerebral pressure stays within ___-___mmHg, then autoregulation maintains pressure in the brain
50-150 mmHg (60-160)
A reduction in cerebral perfusion pressure too low can cause ___________.
Cerebral ischemia

For every 1 mm Hg decrease in pCO2, CBF decreases by ___________.
1-2 mL/100g/min
Elevate head
Hyperventilate
PaCO2 25-30 mmHg probably best
<20 mmHg: too much vasoconstriction with risk of cerebral ischemia
Drain CSF
Osmotic diuretics
Steroids
Barbiturates, Propofol
-Decreases metabolic rate of the brain
Nitrous oxide leads to ________ CBF and CMRO2
increased
All volatile agents decrease CMRO2, and increase CBF and ICP, rank them from highest to lowest
Halothane > Desflurane > Isoflurane > Sevoflurane
IV anesthetics ___________ CBF and CMRO2, exception is ketamine
decrease
Benzos _________ CMRO2
reduce
N2O may cause tension _____________
pneumocephalus
Intraoperative considerations for ENT surgeries
Blood loss can be hidden in oropharynx, stomach - consider using vasoconstrictor (cocaine) or local anesthetic with epinephrine
Slight hypotension
Common nasal and sinus pathologies
Polyps, deviated septum or infections
Bone Cement (methyl methacrylate) physiological effects
Hypersensitivity/anaphylactic reaction to the acrylic monomer
Reflex bradycardia
Toxic effects of the monomer:
- May produce hypotension when absorbed into the circulatory system
- May enhance the depressant cardiovascular effect of volatile halogenated anesthetic agents
Neurapraxia
a temporary loss of motor and sensory function due to blockage of nerve conduction, usually lasting an average of six to eight weeks before full recovery
A fat embolism may manifest as
decreased ETCO2, decrease SpO2, increased PAP, ST changes, or Rt. heart strain
SSEP
Somatosensory evoked potential (SSEP’s)
What prevents venal caval compression?
Left uterine displacement, puts a wedge under their hip to prevent this

Side effects of pitocin
excessive contraction of the uterus
maternal nausea and bradycardia
uterine rupture
water intoxication
anaphylaxis