Systems Review 2: CNS, ENT, Orthopedics, Obstetrics Flashcards
Percentage of Brain, Blood and CSF?
Normal ICP?
Brain 80%
Blood 12%
CSF 8%
Normal ICP: <15 mmHg (Pressure in brain is too much for blood flow from heart)
Avg. adult brain weighs _____g
O2 consumption is 20% of total body consumption, or ______ml/g/min
1400g (2% of body weight)
- 3ml/100g/min
- 50ml/min total
Normal cerebral blood flow?
Normal: 50 ml/100 Gm/min
15% of cardiac output
As long as the cerebral pressure stays within ___-___mmHg, then autoregulation maintains pressure in the brain
50-150 mmHg (60-160)
A reduction in cerebral perfusion pressure too low can cause ___________.
Cerebral ischemia
For every 1 mm Hg decrease in pCO2, CBF decreases by ___________.
1-2 mL/100g/min
Elevate head
Hyperventilate
PaCO2 25-30 mmHg probably best
<20 mmHg: too much vasoconstriction with risk of cerebral ischemia
Drain CSF
Osmotic diuretics
Steroids
Barbiturates, Propofol
-Decreases metabolic rate of the brain
Nitrous oxide leads to ________ CBF and CMRO2
increased
All volatile agents decrease CMRO2, and increase CBF and ICP, rank them from highest to lowest
Halothane > Desflurane > Isoflurane > Sevoflurane
IV anesthetics ___________ CBF and CMRO2, exception is ketamine
decrease
Benzos _________ CMRO2
reduce
N2O may cause tension _____________
pneumocephalus
Intraoperative considerations for ENT surgeries
Blood loss can be hidden in oropharynx, stomach - consider using vasoconstrictor (cocaine) or local anesthetic with epinephrine
Slight hypotension
Common nasal and sinus pathologies
Polyps, deviated septum or infections
Bone Cement (methyl methacrylate) physiological effects
Hypersensitivity/anaphylactic reaction to the acrylic monomer
Reflex bradycardia
Toxic effects of the monomer:
- May produce hypotension when absorbed into the circulatory system
- May enhance the depressant cardiovascular effect of volatile halogenated anesthetic agents