Systemic sclerosis Flashcards
1
Q
Systemic sclerosis is a condition of unknown aetiology characterised by
A
hardened, sclerotic skin and other connective tissues
2
Q
Limited cutaneous systemic sclerosis
A
Raynaud’s may be the first sign
scleroderma affects face and distal limbs predominately
associated with anti-centromere antibodies
3
Q
subtype of limited systemic sclerosis is CREST syndrome
A
Calcinosis,
Raynaud’s phenomenon,
oEsophageal dysmotility,
Sclerodactyly,
Telangiectasia
4
Q
Diffuse cutaneous systemic sclerosis
A
affects trunk and proximal limbs predominately
5
Q
Diffuse cutaneous systemic sclerosis associated with
A
anti scl-70 antibodies