Carcinoma Of skin

Question 1

common variant of skin cancer is ?

Answer 1

Squamous cell cancer

Question 2

Risk factors include for squamous cell cancer?

Answer 2

excessive exposure to sunlight / psoralen UVA therapy

actinic keratoses and Bowen’s disease

immunosuppression e.g. following renal transplant, HIV

smoking

long-standing leg ulcers (Marjolin’s ulcer)

genetic conditions e.g. xeroderma pigmentosum (a hereditary condition characterized by extreme sun sensitivity)

oculocutaneous albinism

Question 3

What is actinic keratosis ?

Answer 3

Actinic, or solar, keratoses (AK) is a common premalignant skin lesion that develops as a consequence of chronic sun exposure

Question 4

Features of actinic keratosis?

Answer 4

small, crusty or scaly, lesions

may be pink, red, brown or the same colour as the skin

typically on sun-exposed areas e.g. temples of head

multiple lesions may be present

Question 5

Clinical feature of squamous cell carcinoma if skin ?

Answer 5

typically on sun-exposed sites such as the head and neck or dorsum of the hands and arms

rapidly expanding painless, ulcerate nodules

may have a cauliflower-like appearance

there may be areas of bleeding

(If on the lip -persistent indurated ulcerating lower lip lesion)