Systemic Lupus Erythematosus

Question 1

What is Systemic Lupus Erythematosus (SLE)?

Answer 1

An autoimmune disease in which atypical immune response results in chronic inflammation and destruction of healthy tissue

Question 2

What are common systemic complications for SLE?

Answer 2

Heart Failure
Renal Failure

Question 3

What are risk factors for developing SLE?

Answer 3

Genetics
Females 20-40 yrs
Ethnicity (basically non-white)

Question 4

What are the signs and symptoms of SLE?

Answer 4

Butterfly rash (malar rash)
Pancytopenia
Raynauds
Fatigue, malaise, weakness
Joint pain, swelling, tenderness
Alopecia
Oral lesions
Anorexia/weight loss
Blurred vision

Question 5

What is the treatment for SLE?

Answer 5

NSAIDs
Steroids
Immunosuppressive agents methotrexate
Antimalarial drug hydroxychloroquine

Question 6

What constitutes a flare up of SLE?

Answer 6

a flare up is a period of exacerbation

Question 7

How to avoid SLE flare ups

Answer 7

Limit UV and prolonged sun exposure
Decrease stress
Avoid infections
Consult with provider before starting new medications/supplements

Question 8

Patient education for SLE?

Answer 8

Protection from the sun (sunscreen, wide-brimmed hat, long-sleeved shirt)
Report evidence of infection
Avoid crowds, sick people
Must be in remission for 6 months before considering pregnancy
Use mild protein shampoo and avoid harsh hair treatments
Avoid ETOH
Understand the effects of disease on lifestyle