Systemic Diseases

Question 1

Polyarteritis Nodosa

Answer 1

mononeuropathy multiplex, seizures, stroke

Question 2

Churg-Strauss

Answer 2

mononeuropathy multiplex, encephalopathy, stroke, chorea

Question 3

giant cell arteritis

Answer 3

HA, blindness, polyneuropathy, stroke

Question 4

Wegener’s granulomatosis

Answer 4

mononeuropathy multiplex, cranial neuropathy, basal meningitis

Question 5

rheumatoid arthritis

Answer 5

myelopathy

Question 6

sjogren syndrome

Answer 6

sensory polyneuropathy

Question 7

behcet disease

Answer 7

aseptic meningoencephalitis

Question 8

cryoglobulinemia

Answer 8

TIA, stroke, peripheral neuropathy

Question 9

DIC

Answer 9

encephalopathy

Question 10

TTP

Answer 10

encephalopathy, sz, stroke

Question 11

whipple disease

Answer 11

dementia, sz, myoclonus, ataxia, supranuclear ophthalmoplegia, oculomasticatory myorhythmia

Question 12

sarcoid

Answer 12

facial and optic nerves affected, meningoencephalitis

Tx: steroids

Question 13

DM

Answer 13

Distal primarily sensory polyneuropathy

hyperglycemia - sz, focal neuro deficits, transient painful periph neuropathy, chorea, stroke

Question 14

marchiafava-bignami syndrome

Answer 14

frontal type dementia, sz, pyramidal signs, focal demyelination and necrosis of corpus callosum from alcohol

Question 15

SLE

Answer 15

psychosis and depression, sz, stroke, HA, chorea, transverse myelitis
distal sensory polyneuropathy

Question 16

pickwickian syndrome

Answer 16

obesity with hypersomnia, hypoxemia and pulmonary HTN, smoking increases risk of developing syndrome, leads to sleep attacks

Question 17

hypothyroidism

Answer 17

HA, dementia, psychosis, decreased consciousness, myopathic weakness and delay in relaxation phase of reflexes
possible cerebellar ataxia