System Review Flashcards
preeclampsia
neuro: AMS, H/A, visual, cerebral edema, seziure, intracranial hemorrage #1 cause death
cardiac: HTN, elevated SVR, hypovolemia
pulm: airway edema, pulm edema (increase PCWP, decreased CO, excess fluid admin)-low colloid oncotic pressure and increase vascular perm predipose
GI: capsule distention, hemorrage, rupture, HELLP
renal: oliguria (decrease GFR), proteinuria from increase glomerular perm
heme: plt activation <100K, hypocoag, increased fibrinolysis
fetal: IUGR, decreased uteroplacnetal perfusion (placental infarcts), premature, abruption
Pregnancy for non-OB surgery
Neuro: decreased MAC and increased sensitivity to LA
cards: aortocaval compression predisposing to hypotension
pulm: difficult airway, low FRC predisposing to desaturation
GI: aspiration risk
Fetal: teratogencity (postnatal changes function or form, weeks 1-6), spontaneous abortion, premature labor, fetal mortality
Heme: thromboembolism
Evaluate the nature of cardiac dz
- FocusedHistory: -known diagnosis, past evaluations/hospitalizations, tests, meds/compliance
- cardiac sx (past and current): exercise tolerance, CP, SOB, syncope, orrthopnea, palpitations - PE: signs for HF -Rhythm, murmurs, S3 gallop, crackles, edema, JVD
3: Labs: CXR EKG, echo
HTN consideration head to toe
perioperative risks,
preop assessment
potential causes
Head to toe
neuro: shift in cerebral autoregulation, stroke, retinopathy
cards: LVH, CAD/MI, arrythmia, CHF (diastolic dys)
renal: overactivity of renin angiotensin-aldosterone system
concerns : BP instability, arrythmias, MI, stroke, CHF, hypoperfusion/end organ ischemia w reduction
Preop:
History:
- cause (essential, coartation aorta, OSA/obesity renal, endocrine-pheo, hyperaldosterone, cushing, pheo, thyroid/parathyroid),
- degree of control, baseline, meds
- end organ effects
PE: signs CHF
Labs: BUN/Cr-renal involement, NA K diruetic effects
EKG for LVH, arrythmia, ischemia, strain
CXR: cardiomegaly, pulm edema
Goal: keep BP within 20% of baseline
Concerns for a aneursym repair
Anesthesia
Difficult airway-
compression (airway compression, SVC syndrome edma), DLT
Cross clamp
neuro
Paraplegia- Loss sensory and motor with intact vibration and proprioception (ASA syndrome); epidural hematoma if neuraxial performed
Stroke: emboli, hypotension
CV
Aneurysm: rupture, thrombosis, compression (SVC, AI MI, CHF
Pulm
Post op pulmonary dysfxn from manipulation of diaphragm and lungs
Damage to phrenic or RLN
Heme
Coagulopathy: activation of coagulation (aneurysm thrombogenic), DIC
dilution effects of massive transfusion,
Renal
Post op AKI
hypotension…what do you do
- 100% oxygen
- confirm adequate ventilation and oxygenation (PTX, broncospasm, anaphlaxisis)
- evaluate monitors
- EKG: look for ischemia, hyperK, hypoCa, and arrythmia
- PIP, PEEP, MV, capnography (broncospasm, anaphalaxsis) - treat with fluids blood pressors PRN
- more access/monitors
- continue to eval cause
obesity
o Anesthesia: difficult airway management, patient positioning, altered drug effects (sensitivity), sensitivity to anesthetics, BP cuff
neuro: stroke, obesity hypoventilation syndrome,
CV: difficulty eval cardipulm status 2/2 sedentary lifestyle, HTN, CAD, phtn,
Pulm: rapid desat w apnea (decreased FRC, high v02), OSA/pickwickian, post op apnea, restrictive lung dz, pHTN
GI: nonalcoholic fatty liver, GERD w abdomen pushing belly up, delayed gastric emptying
Endocrine: DM o
Heme: DVT/PE, wound infection
Types of apnea
apnea
hypoapnea
obesity hyoventilation syndrome
- apnea cessation airflow >10 sec w >4% drop sat, >5 per hr
- hypoapnea >50% cessation in airflow, >4% drop sat, >15/ hr
- OHS 2/2 obesity/OSA: BMI>30, daytime arterial hypercapnea >45 nocternal hypoxia, polycythemia
- Pickwickian: severe form OHS chronic hypovent –>pulm HTN and RVF
hypothermia
neuro: AMS, delayed awaking
Cardiac;: myocardial depression, vasoconstriction (increased epi/NE levels), shivering (increased O2 consumption,increased PVR
Heme: left shift of hgb-O2 dissociation curve, plt dysfunction, poor wound healing/infection
other: decreased drug metabolism
burns
Anesthesia:increase free fraction opioid benzos, 25-30% burns resistance to NDMB at 72 hr, increased binding to alpha 1 glycoprotein, increased fetal Ach R (resistant to NDM
Neuro: head injury
Cards: hypovolemic-leaky capillaries (Parkland)
pulm: inhalational injury–>VQ mismatch, CO posioning (cooximetry) edema
GI: curling ulcer, aspiration risk
Heme: infectionsepsis/ disrupted skin barrier
Machine check
- check for emergeny ventilation equiptment: ambu suction
- check high pressure system: cylinders (1/2 full: 1000PSIG) and pipeline pressures (50-55 PSIG)
- check low pressure system: (vaporizers filled and caps tight, flowmeters cant deliver hypoxic mixture and tested through full range, negative pressure test (bulb to common gas outlet >10 sec)
- check scaavangeing: connection of APL to scavaneging system, NPRV: apl open and O2 flow low should collapse and gausge read 0, PPRV: APL open and and flush O2, bag should distent and read no more than 10 cm H20
- check breathign system: calibrate O2 monitor to RA and 100% oxyegn, inspect ciruit and CO2 absorber, Postive pressure leak test circuit (>30 10 seconds)
- check bmanual and automated breathign system: place bag on Y piece and set paremeters for pt, check this under manual and automated ventilation
- monitors
- machine final position: APL open, vaporizer off, flow off, manual vent selected
Liver disease
o Neuro: 1. Wernicke encephalopathy (ETOH thiamine def) 2. hepatic encephalopathy (production ammonia by intestinal bacteria)
o Pulm: 1. ascites decrease FRC 2. portopulmonary HTN 3. HPS
o GI; increased risk aspiration
o Renal: hepatorenal syndrome
o Heme: 1. SBP 2. plt dysfunction 3. coagulopathy
cirrhosis
heapatic necrosis, fibrosis, and nodal regeneration/ leading to portal HTN >10mmHg. causes ETOH, hepatitis, toxins
Anesthesia:
1) paralysis: may need more larger initial dose due to larger VD, decreaed proetin binding larger free fraction may off set this, and impaired metabolism few doses may be needed
2) citrate intoxication more likely w blood
3) psueocholinesterase def
Neuro: encephalopathy AMS, asterxisis, hyperreflexa, wernicke korsakoff (more permeable BBB, ammonia broken down from blood in GI tract or transfusion)
Cards: hyperdynmaic state =high mixed venous(increased CO, low SVR, anemia, systemic shunts), systemic AV shunts
resp: decreased FRC and restrictive dz from ascites, increased AV shunts, plerual effusions, inhibition of HPV (from vasodilating substances - VIP, glucagon)–>hypoxemia, resp alkalosis
GI: Portal HTN
ascities (2/2 portal HTN, hypoalbumin, renal rentention of fluids)
varices/hemorrhids,
aspiration risk, delayed gastric emptying
renal: decrease renal perfusion, sodium retentiom. (increase in total body andvolume but decrease in effective volume, HRS (prerenal oliguria w NA retention, azotemia, and ascites
Heme: thrombocytopenia (splenic sequestration), anemia (bleeding, RBC destruction, malnutritio) SBP
Electrolytes: hyponatremia (dilutional), hypokalemia (diuresis or hyperaldosteronism), hypoalbumin, hypoglycemia
esophageal cancer
cardio: often after ETOH and smoker, high risk post op a fib
pulm: smokers often, chronic aspiration–>pulm fibrosis,
GI: nutrional status poor (increased MM), liver fxn, aspiration risk (obstruction, altered motility and spincter dysfunction
chemo: doxorubicin (cardiomyopathy, belomycin lung, radiation (pnumonitis, pericarditis
chronic alcoholic
Anesthesia: intoxiciation effect on MAC
neuro: AMS, encephalopathy, wernicke korsaoff (ataxia, confusion, occular issues; tx thiamine), withdrawl (sezizures DT)
cards: acute HTN tachy; cardiomyopathy, arrythmia
resp: smoker?
gi: ulcer, cirrhosis, aspiration risk
heme: pancytopenia
RA
CV: pericardial thickening/pericarditis//effusion, myocarditis/fibrosis, vasculitis, AR, CAD from steriods, conduction defects, vasculitis
pulm: pleural effusion, pulm nodules, pulm fibrosis
Heme: anemia, Aspirin induced plt dysfxn, thrombocytopenia,
endocrine: adrenal insufficiency (chronic steriod use), immunesuppression from steriods and antiinflammatory meds
Joint involvement/difficult intubation: cervical spine (alantoaxial subluxation, >5mm alanto odontoid distance), TMJ, cricoarytenoid joint (hoarse voice, small ETT)= difficult intubation
liver and kidney dysfunction
Ankylosing spondylosis
neuro: nerve root compression, cauda equina syndrome, uvetitis, parathesia, high block 2/2 smaller epidural space, c spine/TMJ involvement
cards: AI, condution defects,
resp: restrictive lung dz, impossible trach if stuck in neck flexion, difficult airway
gi: UC, crohns
SS head to toe
CNS: cerebral thrombosis, painful/vasoocclusive crises, deficits from stoke/seizures
Cardiac: CHFfrom chronic hypoxia, hemochromatosis, MI,
pulm: increased intrapulm shunting, ACS
GI: nonconjugated hyper bili from hemolysis, bile cholelithaisis,
renal: meduallary infarcts leading to isothenuria
Heme: splenic infarcts, aspetic necrosis, osteo, infection (asplenic), aplastic anemia(Parovovirus/folate decreased rbc production+ reduced life span (20 vs 120 days)–>profound anemia), transfusion, anemia
Endocrine: hemachromatosis-DI, hepatomegaly, adrenal insufficiency, hypothyroidism, hypopara
risks factors for aspiration
delayed gastric emptying: autonomic neuopathy, acute abdomen, pain, cirrhosis, chronic alcohol abuse,
pregnancy
bowel obstruction
GERD
DM
Neuro: peripheral neuropathy, retiniopathy
Cards: autonomic neuropathy: silent MI, resting tachycardia, lack HR varibility w respirations, orthostasis, insensitivity to atropine and propranolol, lack HR response to hypovolemia, impaired vasoconstriction (susceptible to hypothermia), lack sweating, impotence
CAD, HTN, cardiomyopathy, PVD, MI
Resp: difficult intubation stiff join syndrome (TMJ, AO, cervical spine-prayer sign)
GI: gastroparesis (early satiety)
renal: nephropathy
endocrine: hyper/hypoglycemia, DKA, NKHC
Heme: impaired phagocytosis
stridor after thyroidectomy
Post extubation airway obstruction/ stridor
Hematoma
Edema
Post intubation croup
Tracheolamacia
laryngospasmm
RLN injury-partial hoarseness, complete-aphonia, aspiration risk b/l partial laryngeal obstruction (abduction of VC)
Hypocalcemia removal of parathyroid 1-3 days later
Residual paralysis (MG common in hyperthyroid pts)