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Drafts > Syphilis > Flashcards

Syphilis Flashcards

1
Q

definition of Syphilis

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2
Q

What does definition of Syphilis respond to?

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3
Q

Causative organism of Syphilis

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4
Q

Shape of Treponema pallidum

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4
Q

Motility of Treponema pallidum

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5
Q

Staining of Treponema pallidum

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5
Q

Culture of Treponema pallidum

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5
Q

Fragility of Treponema pallidum

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6
Q

Types of Treponemes

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7
Q

Why should examination for oral lesions in syphilis be avoided?

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7
Q

Pathogenesis of syphilis

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7
Q

How does Treponema palidum enter the body?

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8
Q

First lesion in syphilis after it enters the body

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9
Q

what happens after Treponema palidum enters the body through skin?

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10
Q

How does someone infected by Treponema palidum enter 3ry stage?

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11
Q

what happens at the end of latent phase of infection by Treponema palidum?

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12
Q

Is there long standing immunity to Treponema palidum?

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13
Q

Natural course of untreated syphilis

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14
Q

IP of syphilis

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15
Q

when soes chancre appear in syphilis?

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16
Q

Healing of chanvre of syphilis

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16
Q

when does secondry stage of syphilis occur?

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17
Q

Results of Serological tests in early latent syphilis

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18
Q

Histopathology of Syphilis

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18
Q

Endarteritis obliterans in syphilis

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19
Q

what doesEndarteritis obliterans in syphilis cause?

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20
Q

Perivascular infiltration in syphilis

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21
Q

Fibroblast activity in syphilis

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21
Q

Time of perivascular infeltration

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22
Q

Time of fibroblast activity

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23
Q

Introduction to Serological Tests of Syphilis

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24
Q

Types of Serological Tests of Syphilis

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25
Q

What do Non-treponemal or reagin tests (Non-specific) measure?

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26
Q

Types of Non-treponemal or reagin tests (Non-specific)

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27
Q

Examples of Flocculation or precipitation tests

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27
Q

Example of Complement fixation tests

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27
Q

when do Reagin tests become positive?

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28
Q

Results of VDRL in 2ry syphilis

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29
Q

Specificity of reagin tests for syphilis

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29
Q

Results of VDRL in 3ry syphilis

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30
Q

Follow up for syphilis using VDRL

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31
Q

Is Serological result for syphilis affected by effective therapy in early stages?

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32
Q

what do Treponemal tests (specific) measure?

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32
Q

Examples of Treponemal tests (specific)

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33
Q

Results of Treponemal tests (specific)

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34
Q

Value & Importance of serological tests of syphilis

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35
Q

Diagnosis of syphilis via serological tests of syphilis

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36
Q

Follow up for syphilis via serological tests of syphilis

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37
Q

what are Biological false positive (BFP) reactions for syphilis?

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38
Q

Definition of Acute BFP reactions for syphilis

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39
Q

Examples of Acute BFP reactions for syphilis

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40
Q

Def of Chronic BFP reactions for syphilis

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41
Q

Examples of Chronic BFP reactions for syphilis

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42
Q

Serologic test for syphilis in patients with HIV

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43
Q

Identification of Syphilis

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44
Q

DG examination in syphilis

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44
Q

Stained smeares in syphilis

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45
Q

EM of syphilis

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46
Q

Classification od syphilis

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47
Q

Stages of Acquired syphilis

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48
Q

Phases of Early stge of Acquired syphilis

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49
Q

Characters of Early stage of Acquired syphilis

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50
Q

Phases of Late stage of Acquired syphilis

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51
Q

Characters of Late stage of Acquired syphilis

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52
Q

Stages of Prenatal (congenital) syphilis

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53
Q

Main stages of Acquired Syphilis

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54
Q

MOI by Acquired Syphilis

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55
Q

Venereal route as a MOI by Acquired Syphilis

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56
Q

NON-Venereal route as a MOI by Acquired Syphilis

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57
Q

Can T.Pallidum penetrate skin, or mucus membrane?

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58
Q

IP of Acquired Syphilis

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59
Q

What does IP of Acquired Syphilis depend on?

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59
Q

Diagnostic Hallmark of Primary Syphilis

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60
Q

Definition of Chancre

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61
Q

Characters of Chancre

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62
Q

Duration of Chancre

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63
Q

Site of Chancre

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64
Q

Regional LNs In Chancre

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64
Q

How should Any painless genital ulcer be considered?

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65
Q

Special types of Chancres

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66
Q

Kissing chancres

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67
Q

Condom chancre

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68
Q

Concealed (Hidden) chancre

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69
Q

Phagedenic chancre

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70
Q

Diagnosis of chancre

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70
Q

Fate of primary syphilis

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71
Q

Investigations of primary syphilis

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72
Q

Identification of T. pallidum

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73
Q

Dark field microscopy in Diagnosis of Syphilis

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74
Q

Indirect fluorescent antibody test in diagnosis of syphilis

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75
Q

Serological tests in old chancre

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76
Q

DDx of Syphilis

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77
Q

Compare between Chancre & Chancroid

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78
Q

When does Secondary Syphilis appear?

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79
Q

Clinical Manifestations of Secondary Syphilis

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80
Q

Incidence of Skin rash (syphilides)

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80
Q

Characters of Skin rash (syphilides)

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81
Q

Number of eruptions of Skin rash (syphilides)

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82
Q

Types of skin rash in Skin rash (syphilides)

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83
Q

Course of Skin rash (syphilides)

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84
Q

Site of Condyloma lata (syphilitic moist papules)

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85
Q

Shape of lesions in Condyloma lata (syphilitic moist papules)

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86
Q

What is the most infectious lesion of 2ry syphilis?

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86
Q

Site of Mucous patches of syphilis

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86
Q

DDx of Condyloma lata (syphilitic moist papules)

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87
Q

Shape of Mucous patches of syphilis

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88
Q

what do Mucous patches of syphilis in the urethra cause?

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89
Q

DDx of secondary syphilis

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89
Q

LNs affection in sypjilis (2ry syphilis)

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90
Q

Other feature sof 2ry syphilis

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91
Q

Fate of 2ry syphilis

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92
Q

Types of Relapse in Relapsing Syphilis

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92
Q

Def of Relapsing Syphilis

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93
Q

Time of Relapsing Syphilis

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94
Q

Types of Relapsing Syphilis

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95
Q

what is the most common type of Relapsing Syphilis?

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96
Q

Chancre redux

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97
Q

Serological relapse

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98
Q

Other types of relapse

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99
Q

Time of Latent Syphilis

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100
Q

Diagnosis of Latent Syphilis

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100
Q

Clinical manifestations of Latent Syphilis

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101
Q

Latent syphilis is divided into ……

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102
Q

Characters of Early latent syphilis

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103
Q

Characters of Late latent syphilis

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103
Q

Duration of Late (Tertiary) Syphilis

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104
Q

Tertiary syphilis includes ….

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105
Q

Quaternary syphilis encompasses …..

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106
Q

Time of Benign Tertiary Syphilis

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107
Q

Characteristic lesion of Benign Tertiary Syphilis

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108
Q

what lesions does Benign Tertiary Syphilis include?

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108
Q

Classiification of gumma

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109
Q

Gumma of skin

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110
Q

Gummata of mucus membranes

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110
Q

Gummata of internal organs

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111
Q

Gummata of Liver

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112
Q

Gummata of stomach

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113
Q

Gummata of testicles

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114
Q

Paroxysmal cold haemoglobinuria (PCH)

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114
Q

Gummata of bones

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115
Q

Gummata of joints

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116
Q

Diagnosis of syphilitic gumma

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117
Q

Incidence of Neurosyphilis

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117
Q

Clinical Manifestations of Neurosyphilis

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118
Q

Why diagnosis of latent syphilis cannot be made unless asymptomatic neurosyphilis is excluded by a negative cerebrospinal fluid examination?

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119
Q

Features of Neurosyphilis

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120
Q

Prognosis of Neurosyphilis

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120
Q

Clinical manifestations of Cardiovascular Syphilis

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121
Q

Incidence of Cardiovascular Syphilis

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122
Q

Dx of Cardiovascular Syphilis

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122
Q

Prognosis of Cardiovascular Syphilis

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123
Q

Prevention of Prenatal (Congenital) Syphilis

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123
Q

Clinical Manifesttaions of Prenatal (Congenital) Syphilis

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123
Q

Def of Prenatal (Congenital) Syphilis

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124
Q

Characters of Early prenatal syphilis

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124
Q

Time of Early prenatal syphilis

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125
Q

Lesions in Early prenatal syphilis

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126
Q

General features in Early prenatal syphilis

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126
Q

Skin lesions in Early prenatal syphilis

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127
Q

Mucus membrane lesions in Early prenatal syphilis

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128
Q

Condyloma lata in Early prenatal syphilis

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129
Q

Dx of Early prenatal syphilis

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130
Q

Characters of Late prenatal syphilis

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130
Q

Time of Late prenatal syphilis

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131
Q

Types of Late prenatal syphilis

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132
Q

Characters of Late latent (asymptomatic) congenital syphilis

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132
Q

What is the most common character of Late symptomatic congenital syphilis?

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133
Q

Caracters of Late symptomatic congenital syphilis

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134
Q

Neurosyphilis in Late symptomatic congenital syphilis

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135
Q

Skin & MM Lesions in Late symptomatic congenital syphilis

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135
Q

Bone involvment on Late symptomatic congenital syphilis

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135
Q

Dx of Late symptomatic congenital syphilis

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136
Q

Def of Stigmata of prenatal syphilis

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136
Q

Types of Stigmata of prenatal syphilis

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136
Q

CP of Stigmata of early lesions

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137
Q

CP of Stigmata of late lesions

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138
Q

what is Hutchinson’s triad?

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138
Q

Dx of prenatal Congenital syphilis

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139
Q

Intro to Managment of Syphilis

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140
Q

✨……….✨is the drug of choice in all stages of the disease

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140
Q

Penicillin treatment regimens for acquired syphilis

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141
Q

Alt. TTT of Early acquired syphilis (primary, secondary, and early latent)

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141
Q

Alternative treatment Late latent and unknown duration, cardiovascular and gummatous syphilis; retreatment of primary, secondary or latent syphilis after failed initial treatment

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141
Q

What does Treatment regimens for congenital syphilis depend on?

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142
Q

TTT of Congenital Syphilis in cases of Normal CSF

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142
Q

TTT of Congenital Syphilis in cases of abnormal CSF

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143
Q

TTT of Congenital syphilis in children over the age of 15

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144
Q

Def of Jarisch-Herxheimer reaction

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144
Q

What are treatment reactions in syphilis?

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145
Q

Def of Therapeutic paradox

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145
Q

Duration of Jarisch-Herxheimer reaction

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145
Q

Mechanism of Jarisch-Herxheimer reaction

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145
Q

Managment of Jarisch-Herxheimer reaction

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146
Q

Types of Penicillin reactions

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147
Q

Def of Procaine reaction

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147
Q

Def of Vasovagal attack (faint)

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