Syphilis Flashcards
(196 cards)
1
Q
definition of Syphilis
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2
Q
What does definition of Syphilis respond to?
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3
Q
Causative organism of Syphilis
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4
Q
Shape of Treponema pallidum
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4
Q
Motility of Treponema pallidum
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5
Q
Staining of Treponema pallidum
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5
Q
Culture of Treponema pallidum
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5
Q
Fragility of Treponema pallidum
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6
Q
Types of Treponemes
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7
Q
Why should examination for oral lesions in syphilis be avoided?
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7
Q
Pathogenesis of syphilis
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7
Q
How does Treponema palidum enter the body?
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8
Q
First lesion in syphilis after it enters the body
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9
Q
what happens after Treponema palidum enters the body through skin?
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10
Q
How does someone infected by Treponema palidum enter 3ry stage?
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11
Q
what happens at the end of latent phase of infection by Treponema palidum?
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12
Q
Is there long standing immunity to Treponema palidum?
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13
Q
Natural course of untreated syphilis
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14
Q
IP of syphilis
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15
Q
when soes chancre appear in syphilis?
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16
Q
Healing of chanvre of syphilis
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16
Q
when does secondry stage of syphilis occur?
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17
Q
Results of Serological tests in early latent syphilis
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18
Q
Histopathology of Syphilis
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18
Endarteritis obliterans in syphilis
19
what does**Endarteritis obliterans** in syphilis cause?
20
Perivascular infiltration in syphilis
21
Fibroblast activity in syphilis
21
Time of perivascular infeltration
22
Time of fibroblast activity
23
Introduction to **Serological Tests of Syphilis**
24
Types of Serological Tests of Syphilis
25
What do **Non-treponemal or reagin tests (Non-specific)** measure?
26
Types of **Non-treponemal or reagin tests (Non-specific)**
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Examples of Flocculation or precipitation tests
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Example of Complement fixation tests
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when do Reagin tests become positive?
28
Results of VDRL in 2ry syphilis
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Specificity of reagin tests for syphilis
29
Results of VDRL in 3ry syphilis
30
Follow up for syphilis using VDRL
31
Is Serological result for syphilis affected by effective therapy in early stages?
32
what do Treponemal tests (specific) measure?
32
Examples of Treponemal tests (specific)
33
Results of Treponemal tests (specific)
34
Value & Importance of serological tests of syphilis
35
Diagnosis of syphilis via serological tests of syphilis
36
Follow up for syphilis via serological tests of syphilis
37
what are **Biological false positive (BFP) reactions** for syphilis?
38
Definition of Acute BFP reactions for syphilis
39
Examples of Acute BFP reactions for syphilis
40
Def of Chronic BFP reactions for syphilis
41
Examples of Chronic BFP reactions for syphilis
42
Serologic test for syphilis in patients with HIV
43
Identification of Syphilis
44
DG examination in syphilis
44
Stained smeares in syphilis
45
EM of syphilis
46
Classification od syphilis
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Stages of **Acquired syphilis**
48
Phases of Early stge of **Acquired syphilis**
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Characters of Early stage of **Acquired syphilis**
50
Phases of Late stage of **Acquired syphilis**
51
Characters of Late stage of **Acquired syphilis**
52
Stages of **Prenatal (congenital) syphilis**
53
Main stages of **Acquired Syphilis**
54
MOI by Acquired Syphilis
55
Venereal route as a MOI by Acquired Syphilis
56
NON-Venereal route as a MOI by Acquired Syphilis
57
Can T.Pallidum penetrate skin, or mucus membrane?
58
IP of **Acquired Syphilis**
59
What does IP of **Acquired Syphilis** depend on?
59
Diagnostic Hallmark of **Primary Syphilis**
60
Definition of **Chancre**
61
Characters of Chancre
62
Duration of **Chancre**
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Site of **Chancre**
64
Regional LNs In **Chancre**
64
How should Any painless genital ulcer be considered?
65
Special types of Chancres
66
Kissing chancres
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Condom chancre
68
Concealed (Hidden) chancre
69
Phagedenic chancre
70
Diagnosis of chancre
70
Fate of primary syphilis
71
Investigations of primary syphilis
72
Identification of T. pallidum
73
Dark field microscopy in Diagnosis of **Syphilis**
74
Indirect fluorescent antibody test in diagnosis of syphilis
75
Serological tests in old chancre
76
DDx of Syphilis
77
Compare between Chancre & Chancroid
78
When does **Secondary Syphilis** appear?
79
Clinical Manifestations of Secondary Syphilis
80
Incidence of Skin rash (syphilides)
80
Characters of Skin rash (syphilides)
81
Number of eruptions of Skin rash (syphilides)
82
Types of skin rash in **Skin rash (syphilides)**
83
Course of **Skin rash (syphilides)**
84
Site of **Condyloma lata (syphilitic moist papules)**
85
Shape of lesions in Condyloma lata (syphilitic moist papules)
86
What is the most infectious lesion of 2ry syphilis?
86
Site of **Mucous patches of syphilis**
86
DDx of **Condyloma lata (syphilitic moist papules)**
87
Shape of **Mucous patches of syphilis**
88
what do Mucous patches of syphilis in the urethra cause?
89
DDx of secondary syphilis
89
LNs affection in sypjilis (2ry syphilis)
90
Other feature sof 2ry syphilis
91
Fate of 2ry syphilis
92
Types of Relapse in **Relapsing Syphilis**
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Def of **Relapsing Syphilis**
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Time of **Relapsing Syphilis**
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Types of **Relapsing Syphilis**
95
what is the most common type of **Relapsing Syphilis**?
96
Chancre redux
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Serological relapse
98
Other types of relapse
99
Time of Latent Syphilis
100
Diagnosis of **Latent Syphilis**
100
Clinical manifestations of **Latent Syphilis**
101
Latent syphilis is divided into ......
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Characters of **Early latent syphilis**
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Characters of **Late latent syphilis**
103
Duration of **Late (Tertiary) Syphilis**
104
Tertiary syphilis includes ....
105
Quaternary syphilis encompasses .....
106
Time of Benign Tertiary Syphilis
107
Characteristic lesion of **Benign Tertiary Syphilis**
108
what lesions does **Benign Tertiary Syphilis** include?
108
Classiification of gumma
109
Gumma of skin
110
Gummata of mucus membranes
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Gummata of internal organs
111
Gummata of Liver
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Gummata of stomach
113
Gummata of testicles
114
Paroxysmal cold haemoglobinuria (PCH)
114
Gummata of bones
115
Gummata of joints
116
Diagnosis of syphilitic gumma
117
Incidence of **Neurosyphilis**
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Clinical Manifestations of **Neurosyphilis**
118
Why diagnosis of latent syphilis cannot be made unless asymptomatic neurosyphilis is excluded by a negative cerebrospinal fluid examination?
119
Features of **Neurosyphilis**
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Prognosis of **Neurosyphilis**
120
Clinical manifestations of **Cardiovascular Syphilis**
121
Incidence of **Cardiovascular Syphilis**
122
Dx of Cardiovascular Syphilis
122
Prognosis of **Cardiovascular Syphilis**
123
Prevention of **Prenatal (Congenital) Syphilis**
123
Clinical Manifesttaions of Prenatal (Congenital) Syphilis
123
Def of **Prenatal (Congenital) Syphilis**
124
Characters of **Early prenatal syphilis**
124
Time of **Early prenatal syphilis**
125
Lesions in **Early prenatal syphilis**
126
General features in **Early prenatal syphilis**
126
Skin lesions in **Early prenatal syphilis**
127
Mucus membrane lesions in **Early prenatal syphilis**
128
Condyloma lata in **Early prenatal syphilis**
129
Dx of **Early prenatal syphilis**
130
Characters of **Late prenatal syphilis**
130
Time of **Late prenatal syphilis**
131
Types of **Late prenatal syphilis**
132
Characters of **Late latent (asymptomatic) congenital syphilis**
132
What is the most common character of **Late symptomatic congenital syphilis**?
133
Caracters of **Late symptomatic congenital syphilis**
134
Neurosyphilis in **Late symptomatic congenital syphilis**
135
Skin & MM Lesions in **Late symptomatic congenital syphilis**
135
Bone involvment on **Late symptomatic congenital syphilis**
135
Dx of **Late symptomatic congenital syphilis**
136
Def of **Stigmata of prenatal syphilis**
136
Types of **Stigmata of prenatal syphilis**
136
CP of Stigmata of early lesions
137
CP of Stigmata of late lesions
138
what is **Hutchinson's triad**?
138
Dx of prenatal Congenital syphilis
139
Intro to Managment of Syphilis
140
✨..........✨is the drug of choice in all stages of the disease
140
Penicillin treatment regimens for acquired syphilis
141
Alt. TTT of Early acquired syphilis (primary, secondary, and early latent)
141
Alternative treatment Late latent and unknown duration, cardiovascular and gummatous syphilis; retreatment of primary, secondary or latent syphilis after failed initial treatment
141
What does Treatment regimens for congenital syphilis depend on?
142
TTT of Congenital Syphilis in cases of Normal CSF
142
TTT of Congenital Syphilis in cases of abnormal CSF
143
TTT of Congenital syphilis in children over the age of 15
144
Def of **Jarisch-Herxheimer reaction**
144
What are treatment reactions in syphilis?
145
Def of **Therapeutic paradox**
145
Duration of **Jarisch-Herxheimer reaction**
145
Mechanism of **Jarisch-Herxheimer reaction**
145
Managment of **Jarisch-Herxheimer reaction**
146
Types of **Penicillin reactions**
147
Def of **Procaine reaction**
147
Def of **Vasovagal attack (faint)**
