Synaptic transmission Flashcards
What are electrical synapses also known as?
Gap junctions
What protein is used to make gap junctions?
Connexin
What are ionotropic neurotransmitter receptors?
Directly linked to ion channels (ligand gated)
What are metabotropic neurotransmitter receptors?
G-coupled receptors
Are meoabotrobic or ionotropic neurotransmitter receptors faster?
Ionotropic
What are the active zones?
Areas on presynaptic membrane in which vesicles are released
What do active zones correspond to?
Receptors on post-synaptic membrane
What do SNARE proteins allow?
Vesicle fusion with terminal membrane
What are V-SNARE proteins?
Vesicle membrane proteins
What are T-SNARE proteins?
Target membrane proteins
How is the fused vesicle cut off from the membrane?
Coated in clathrin and cut off by dyamin
What is temporal summation?
Adding together of EPSPs generated by firing from he same terminal at high frequency
What is spatial summation?
Adding together of EPSPs generated by firing of 2 more more neurones simultaneously
What receptors are activated to from an EPSP?
Na+
What receptors are activated to from an IPSP?
Cl-/K+