synaptic transmission

Question 1

cholinergic synapse

Answer 1

action potential arrives at the presynaptic neurone
depolarising the membrane and causing voltage gated calcium ion channels to open
the influx of calcium ions causes the voltage gated calcium ion channels to open
the calcium ion influx causes the synaptic vesicles to fuse with the membrane releasing the neurotransmitters into the synaptic cleft
the neurotransmitter binds to receptors on post synaptic neurone. this causes an action potential.

Question 2

is cholingeric synapse inhibitory or excitatory

Answer 2

can be excitatory if the neurotransmitter opens Na+ channels or inhibitory is the potassium channels are opened

Question 3

temporal summation

Answer 3

multiple action potentials from a single presynaptic neurone are added together in post synaptic over time.

Question 4

spatial summation

Answer 4

when action potentials from multiple presynaptic neruones are added together in a single post synaptic neurone.

Question 5

what happens at post synaptic neurone

Answer 5

the neurotransmitter diffuses across the synaptic cleft
the neurotransmitter binds to receptors on postsynaptic membrane
sodium ions enter stimulating depolarisation and an action potential in PSN